Category: Endocrine Surgery

Autofluorescence in Thyroidectomy Cuts Hypoparathyroidism Rates

Autofluorescence-guided total thyroidectomy significantly reduced immediate and permanent hypoparathyroidism rates in low-volume, nonparathyroid institutions. Introduction of autofluorescence decreased immediate hypoparathyroidism from 37% to 19% and permanent hypoparathyroidism from 32% to 6%, eventually reaching 0%. More parathyroid glands were identified and fewer inadvertently excised with autofluorescence. These findings suggest that the use of autofluorescence in thyroid […]

Thermal Ablation Matches Lobectomy in Long-Term Outcomes for Thyroid Microcarcinoma

Long-term multicenter study comparing image-guided thermal ablation to lobectomy for solitary papillary thyroid microcarcinoma showed no significant differences in disease progression or survival outcomes. Ablation had lower complication rates, shorter hospitalization, procedure time, reduced blood loss, and lower costs compared to lobectomy. Thermal ablation could be a safe and effective alternative for properly selected patients […]

Beneficial Metabolic Effects of Adrenalectomy in Patients with Mild Autonomous Cortisol Secretion

Adrenalectomy significantly improved body weight, glucose, and blood pressure in patients with mild autonomous cortisol secretion. The study found a higher frequency of improved control in the adrenalectomy group compared to the control group. Factors like adrenalectomy, body mass index, and cortisol levels were associated with better weight control, while adrenalectomy and diabetes were linked […]

Ultrafast Intraoperative Parathyroid Hormone Monitoring System

In a study evaluating an innovative intraoperative parathyroid hormone monitoring system, 96.2% of patients undergoing parathyroidectomy for hyperparathyroidism were cured. The system showed high sensitivity (98.6%) and accuracy (98.6%) in predicting biochemical cure, with no false positives. Strong correlations with conventional devices and improvements in sampling protocols make this system a reliable and efficient tool […]

Conformal Thyroidectomy as a Feasible Option in Papillary Thyroid Microcarcinoma

Conformal thyroidectomy in low-risk PTMC patients showed advantages in perioperative management with reduced hospital stays, shorter operative times, lower complication rates, and comparable event-free survival to lobectomy. It resulted in decreased rates of vocal cord paralysis, hypoparathyroidism, and permanent hypothyroidism. This study supports the use of conformal thyroidectomy as a suitable option for patients unable […]

Time Kinetics and Prognosis Roles of Calcitonin after Surgery for Medullary Thyroid Carcinoma

Time kinetics of calcitonin normalization (CN) and biochemical persistence/recurrence (BP) after surgery for medullary thyroid carcinoma were studied in 190 patients. Early CN predicted long-term risks of recurrence, with lymph node ratio (LNR) being a significant factor. Higher primary tumor size and longer CN time were associated with decreased disease-free survival. Tailored follow-up based on […]

Effectiveness of Ultrasound-Guided Ablation Techniques for Benign Thyroid Nodules

Ultrasound-guided ablation techniques, particularly radiofrequency ablation (RFA), show effectiveness in treating benign thyroid nodules. RFA with 2 sessions is optimal for solid nodules, while polidocanol ablation stands out for cystic nodules. A network meta-analysis of 35 studies involving 5655 patients demonstrated RFA as the most effective method at 12 months, with RFA2 showing strong outcomes […]

Management of Recurrent Laryngeal Nerve Infiltrated by Thyroid Carcinoma

Novel intraoperative phonosurgical management significantly improved voice quality post-surgery in patients with thyroid carcinoma infiltrating the recurrent laryngeal nerve. Resection and arytenoid adduction for medullary thyroid cancer, resection and ansa cervicalis-to-rln anastomosis for well-differentiated thyroid cancer with preoperative paralysis, and rln preservation for patients with normal vocal fold mobility showed promising outcomes. Journal Article by […]

Efficacy of Fibrin Sealants in Thyroidectomy

Researchers conducted a systematic review and meta-analysis of seven randomized controlled trials to evaluate the safety and efficacy of fibrin sealants (FS) in thyroid surgery. The analysis included 652 patients who underwent thyroidectomy with FS and compared them with conventionally treated patients. The primary outcomes were total wound drainage, length of hospitalization, and operative time. […]

Improving Adrenal Incidentaloma Evaluation Through a Quality Improvement Initiative

Implementation of a quality improvement program led to increased primary care provider-initiated evaluation of adrenal incidentalomas, with 35.5% meeting the primary endpoint in the quality improvement cohort compared to 27.6% in the historical cohort. Patients in the quality improvement cohort had 1.70 times higher odds of undergoing primary care provider-initiated evaluation. Adrenal surgery rates did […]