Thyroglobulin wash-out after fine-needle aspiration cytodiagnosis effectively evaluates lymph node metastasis in papillary thyroid carcinoma. A cutoff value of 3.2 ng/ml for FNA-TG offers higher accuracy and lower false negatives than single diagnoses. Combining FNAC with FNA-TG increases sensitivity, though specificity decreases slightly. Ultrasonography provides dynamic LN assessment, enhancing diagnostic efficacy without added patient discomfort. […]
Category: Endocrine Surgery
Ultrasound Predicts Lymphatic Spread in Papillary Thyroid Cancer
Ultrasound features like loss of fatty hilum, architectural distortion, enlarged size, and microcalcifications are associated with metastatic papillary thyroid cancer. A combination of these features shows high specificity and positive predictive value for malignancy. This study suggests a risk stratification model based on these ultrasound characteristics could improve the classification of nodal metastases in patients […]
Shift in Treatment Outcome Valuation for Low-Risk Thyroid Cancer
Patients with low-risk thyroid cancer changed their valuation of treatment outcomes after surgical decisions, favoring quality of life factors post-treatment. Emotional impact led to overuse of total thyroidectomy. Those choosing lobectomy increased importance on risk of recurrence, while total thyroidectomy patients valued it less. Surgeons can better discuss post-surgery effects on energy levels with patients […]
Reduced postoperative sore throat with combined budesonide and dexamethasone
Preoperative inhaled budesonide combined with intravenous dexamethasone significantly decreased postoperative sore throat (post) incidence and severity at 6, 12, and 24 hours in patients undergoing thyroidectomy. Additionally, this combination resulted in lower postoperative coughing rates at 24 hours compared to intravenous dexamethasone alone. Hoarseness outcomes were similar between the two groups. This combination therapy shows […]
Autofluorescence in Thyroidectomy Cuts Hypoparathyroidism Rates
Autofluorescence-guided total thyroidectomy significantly reduced immediate and permanent hypoparathyroidism rates in low-volume, nonparathyroid institutions. Introduction of autofluorescence decreased immediate hypoparathyroidism from 37% to 19% and permanent hypoparathyroidism from 32% to 6%, eventually reaching 0%. More parathyroid glands were identified and fewer inadvertently excised with autofluorescence. These findings suggest that the use of autofluorescence in thyroid […]
Thermal Ablation Matches Lobectomy in Long-Term Outcomes for Thyroid Microcarcinoma
Long-term multicenter study comparing image-guided thermal ablation to lobectomy for solitary papillary thyroid microcarcinoma showed no significant differences in disease progression or survival outcomes. Ablation had lower complication rates, shorter hospitalization, procedure time, reduced blood loss, and lower costs compared to lobectomy. Thermal ablation could be a safe and effective alternative for properly selected patients […]
Beneficial Metabolic Effects of Adrenalectomy in Patients with Mild Autonomous Cortisol Secretion
Adrenalectomy significantly improved body weight, glucose, and blood pressure in patients with mild autonomous cortisol secretion. The study found a higher frequency of improved control in the adrenalectomy group compared to the control group. Factors like adrenalectomy, body mass index, and cortisol levels were associated with better weight control, while adrenalectomy and diabetes were linked […]
Ultrafast Intraoperative Parathyroid Hormone Monitoring System
In a study evaluating an innovative intraoperative parathyroid hormone monitoring system, 96.2% of patients undergoing parathyroidectomy for hyperparathyroidism were cured. The system showed high sensitivity (98.6%) and accuracy (98.6%) in predicting biochemical cure, with no false positives. Strong correlations with conventional devices and improvements in sampling protocols make this system a reliable and efficient tool […]
Conformal Thyroidectomy as a Feasible Option in Papillary Thyroid Microcarcinoma
Conformal thyroidectomy in low-risk PTMC patients showed advantages in perioperative management with reduced hospital stays, shorter operative times, lower complication rates, and comparable event-free survival to lobectomy. It resulted in decreased rates of vocal cord paralysis, hypoparathyroidism, and permanent hypothyroidism. This study supports the use of conformal thyroidectomy as a suitable option for patients unable […]
Time Kinetics and Prognosis Roles of Calcitonin after Surgery for Medullary Thyroid Carcinoma
Time kinetics of calcitonin normalization (CN) and biochemical persistence/recurrence (BP) after surgery for medullary thyroid carcinoma were studied in 190 patients. Early CN predicted long-term risks of recurrence, with lymph node ratio (LNR) being a significant factor. Higher primary tumor size and longer CN time were associated with decreased disease-free survival. Tailored follow-up based on […]
