The liver immune status index (LISI) demonstrated strong predictive capabilities for postoperative outcomes in hepatocellular carcinoma (HCC) patients, particularly with vascular invasion. In a study of 1,337 hepatectomies, LISI effectively stratified patients into distinct risk groups, correlating significantly with established prognostic markers. Notably, LISI provided superior predictive performance for two-year overall survival and recurrence rates. […]
Category: HPB & Spleen
Nomogram Predicts Cancer-Specific Survival in Advanced Liver Cancer
A nomogram designed to predict cancer-specific survival (CSS) in middle-aged patients with advanced hepatocellular carcinoma demonstrated significant accuracy. Analyzing data from 3,026 patients, independent risk factors linked to CSS included gender, marital status, AJCC stage, tumor size, and metastasis. The model achieved area under the curve (AUC) values of 0.74, 0.78, and 0.82 for 1-, […]
Higher mFI-5 scores predict increased mortality in PDAC patients.
In a study of 250 patients with pancreatic ductal adenocarcinoma undergoing pancreatoduodenectomy, higher modified 5-item frailty index (mFI-5) scores were linked to worse surgical outcomes. An mFI-5 score greater than 2 was independently associated with doubled mortality risk (HR 2.08), while median overall survival was significantly lower for those with scores above 2 (21.3 months) […]
Robotic-assisted one-stage management improves outcomes for choledocholithiasis
A recent study highlighted that robotic-assisted laparoscopic cholecystectomy with transcystic common bile duct exploration enables quicker duct clearance and shorter hospital stays. Patients undergoing this one-stage approach experienced significantly lower times for CBD clearance (45.2 hours vs. 47.0 hours), reduced length of stay (3.9 days vs. 5.1 days), and lowered radiation exposure (23.0 mSv vs. […]
Virtual collaboration enables safe robotic pancreatoduodenectomy program
A structured robotic pancreatoduodenectomy (rpd) program was successfully initiated with virtual expert collaboration, demonstrating excellent perioperative outcomes. Over 68 patients underwent the procedure from August 2020 to December 2023, achieving a median operative time of 407 minutes, an estimated blood loss of 150 ml, and 90% negative margins. Notably, the operative time significantly decreased in […]
Stereotactic body radiation therapy shows promise for hepatocellular carcinoma
Stereotactic body radiation therapy (SBRT) has emerged as a viable treatment for hepatocellular carcinoma (HCC), particularly for patients with advanced stages. Recognized in clinical guidelines as effective against alternatives like radiofrequency ablation, SBRT demonstrates local control rates of 80-90%. Its role in downstaging unresectable tumors or as a bridge to transplant is gaining traction, with […]
YAP-based nomogram enhances prognosis prediction in hepatocellular carcinoma
A novel nomogram incorporating YAP expression and clinical metrics has been developed to predict postoperative prognosis in hepatocellular carcinoma (HCC) patients. Researchers evaluated 262 patients post-partial hepatectomy and found that those with high YAP expression faced significantly poorer recurrence-free survival (RFS) and overall survival (OS) rates. The model, validated externally, integrates critical factors like hepatitis […]
Peritoneum to portal vein distance predicts pancreatic fistula risk
A study investigating postoperative pancreatic fistula (POPF) risk factors in 210 distal pancreatectomy patients revealed that a peritoneum to portal vein distance (PPD) of 68 mm serves as a significant predictor for POPF, outperforming the visceral fat area (VFA). Among the identified risk factors, CRP levels and drain amylase on postoperative day three also emerged […]
EUS-CDS with LAMS shows superior success for DMBO treatment
A comparative network meta-analysis revealed that EUS-CDS with lumen-apposing metal stents (LAMS) outperformed other drainage techniques for distal malignant biliary obstruction (DMBO). This method yielded the highest technical and clinical success rates, particularly after comparing with ERCP and EUS-CDS with self-expandable metal stents. Notably, the study recommends discontinuing percutaneous transhepatic biliary drainage (PTBD) as a […]
ICG fluorescence imaging improves laparoscopic cholangiography outcomes
The application of indocyanine green (ICG) fluorescence imaging in laparoscopic bile duct exploration markedly enhanced surgical efficiency. Patients receiving ICG exhibited faster identification of biliary structures, reduced operative time, and shorter postoperative hospital stays compared to those using conventional fiber-optic imaging. Additionally, the ICG group experienced less intraoperative blood loss and fewer incidences of bile […]