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Gland Surg29 Oct 2024

Combined radiomics and body analysis enhance predictive accuracy for pancreatic surgery complications

A new model integrating radiomics, pancreatic duct diameter, and body composition analysis effectively predicts clinically relevant postoperative pancreatic fistula in patients undergoing pancreaticoduodenectomy. This combined approach achieved an area under the ROC curve of 0.839, outperforming existing models. Internal validation through 1,000 bootstrap resamples demonstrated…

HPB & Spleen28 Oct 2024

A nomogram predicts postoperative biliary fistula after pancreaticoduodenectomy.

A novel nomogram has been developed to predict postoperative biliary fistula (PBF) risk after pancreaticoduodenectomy. Analyzing data from 196 patients, researchers identified diabetes, low albumin, postoperative gastroparesis, abdominal bleeding, abdominal infection, and pancreatic fistula as independent risk factors. The model demonstrated good discriminative ability with…

Hepatobiliary Pancreat Dis Int27 Oct 2024

Nomogram effectively predicts severe complications post-surgery after COVID-19

A novel nomogram crafted to forecast severe postoperative complications in elective hepato-pancreato-biliary surgery following COVID-19 breakthrough infections demonstrated high accuracy. The model utilized data from 2,636 patients and identified significant predictors, including timing of surgery relative to the infection and vaccination status. With an area…

Tzu Chi Med J27 Oct 2024

Laparoscopic hepatectomy shows safety and effectiveness for liver cancer

Laparoscopic hepatectomy (LH) emerges as a safe, effective treatment for primary hepatocellular carcinoma (HCC) in favorable locations, as seen in a study involving 159 patients. While LH and open hepatectomy (OH) showed no significant differences in major complications or 90-day mortality, LH reduced transfusion rates,…

J Surg Oncol25 Oct 2024

Minimally invasive liver resection options show safety for colorectal cancer patients

A systematic review and network meta-analysis involving 13 studies and 6,582 patients examined the effectiveness of open, laparoscopic, and robotic liver resections for colorectal liver metastases. Findings indicated no significant differences in R0 resection rates, disease-free survival, or overall survival among the methods. However, laparoscopic…

Ann Surg Oncol24 Oct 2024

Major morbidity and mortality linked to complications post-surgery

Among 2,186 patients undergoing major liver resection for perihilar cholangiocarcinoma, a failure to rescue (FTR) rate of 24% was identified in those with severe complications. Key factors associated with FTR included age, higher ASA classification, jaundice at presentation, right-sided resections, and low annual hospital surgical…

Appendix, Gallbladder and Surgical Emergencies23 Oct 2024

Magnesium supplementation may help prevent acute pancreatitis.

A systematic review of twelve studies reveals magnesium deficiency in pancreatic acinar cells is often linked to reduced serum calcium, predisposing individuals to acute pancreatitis. The research indicates that magnesium acts as a natural calcium antagonist, mitigating intracellular calcium accumulation and premature enzyme activation. Supplementation…

Ann Surg22 Oct 2024

Omitting Abdominal Drains Reduces Complications After Left Pancreatectomy

A systematic review and meta-analysis, including 15,817 patients, reveals that omitting abdominal drainage after left pancreatectomy significantly lowers major morbidity, postoperative pancreatic fistula rates, readmissions, and surgical site infections. The no-drain group demonstrated a relative risk of 0.77 for major complications and a striking 51%…

BMC Surg22 Oct 2024

Surgery improves outcomes in metastatic neuroendocrine tumors

Evidence suggests that surgical intervention, prior to peptide receptor radionuclide therapy, significantly enhances progression-free survival for patients with metastatic gastroenteropancreatic neuroendocrine tumors. In a study of 89 well-matched patients, those who underwent surgery had a median progression-free survival of 26.1 months, compared to 15.6 months…