ERC-related procedures before biliary tract cancer surgery increase the risk of skeletal muscle mass loss. Post-ERC complications like pancreatitis and cholangitis are independent risk factors for large muscle mass decrease. Skeletal muscle mass decreases in most patients with BTC undergoing ERC, highlighting the importance of preoperative assessment and interventions to prevent sarcopenia. Journal Article by […]
Category: HPB & Spleen
Low Progression Rate in Surveilled Side-Branch Intraductal Pancreatic Mucinous Neoplasms
Side-branch intraductal papillary mucinous neoplasms (sb-ipmns) have a low rate (15.3%) of clinically relevant progression (CR-progression), leading to invasive cancer mainly due to size increase or main-duct involvement. Patients with CR-progression benefit from timely resection, but initial size alone is not a reliable indicator for surgery. Non-operative surveillance is crucial, as most surveilled lesions show […]
TPIAT Outcomes Differ by Pancreatitis Etiology
Total pancreatectomy with islet autotransplantation (TPIAT) outcomes in patients with chronic pancreatitis differ based on genetic or nongenetic etiology. Patients with genetic pancreatitis undergo TPIAT at a younger age and have longer symptom duration. Despite lower islet yields, they maintain metabolic function similar to nongenetic patients post-TPAIT. Genetic patients also experience better pain relief and […]
Prognostic Value of Textbook Outcome Score in Pancreatic Surgery
Textbook Outcome Score (TOPS) in pancreaticoduodenectomy for ampullary carcinoma showed a significant 1-year survival benefit, with 34.2% achieving a positive score. TOPS proved valuable in assessing hospital quality metrics and short-term survival, with a 6.3% failure-to-rescue rate. Major complications affected a quarter of patients, highlighting the importance of TOPS as a prognostic indicator in pancreatic […]
AI Revolutionizes Liver Resection Management
Artificial intelligence in perioperative planning and management of liver resection holds immense promise for the future of liver cancer care. AI-driven advancements enable precise tumor detection, patient-specific treatment predictions, enhanced surgical precision, streamlined patient monitoring, and accelerated research development. The integration of AI revolutionizes liver cancer care, offering personalized, efficient, and effective solutions that improve […]
Minimally Invasive Surgery for Pancreatic Neuroendocrine Tumors
Minimally invasive surgery for left pancreatic resection in patients with resectable pancreatic neuroendocrine tumors reduces major complications and offers comparable long-term oncologic outcomes. A study comparing minimally invasive and open surgery showed lower rates of major morbidity, postoperative complications, and better outcomes with minimally invasive surgery. This suggests that minimally invasive surgery can be safely […]
Low Skeletal Muscle Mass Predicts Pancreatic Cancer Surgery Outcomes
Reduction in muscle mass, measured through L3-CT, is common in pancreatic cancer patients undergoing surgery. Preoperative low skeletal muscle index is significantly linked to lower overall survival rates but not to other postoperative outcomes. Evaluating skeletal muscle index preoperatively could help predict patient outcomes, highlighting the importance of nutritional interventions to preserve muscle mass and […]
Superior outcomes of laparoscopic liver resection for NAFLD-associated HCC
Comparing laparoscopic liver resection (LLR) and open liver resection (OLR) for nonalcoholic fatty liver disease-associated hepatocellular carcinoma (NAFLD-HCC), LLR showed lower rates of complications, blood loss, transfusion, and shorter postoperative stay. Both groups had comparable major morbidities and survival outcomes. LLR appears to be a preferred treatment option over OLR for NAFLD-HCC, pending careful patient […]
Sarcopenia Linked to Worse Outcomes in Pancreatic Surgery
High prevalence of sarcopenia and sarcopenic obesity in elderly male patients undergoing pancreatic surgery was associated with increased risk of severe postoperative complications. Visceral obesity and malnutrition did not impact outcomes significantly. Perineural invasion was common but unrelated to body composition. Findings highlight the need for preoperative evaluation of skeletal muscle and tailored interventions to […]
FGFR2 Alterations Enhance Survival in iCCA Patients
Meta-analysis reveals patients with intrahepatic cholangiocarcinoma (iCCA) and FGFR2 alterations have significantly better overall survival outcomes compared to those without. Results suggest FGFR2 alterations could serve as a promising therapeutic target for managing iCCA, especially in cases of metastatic or unresectable tumors. This study presents innovative insights into targeted therapy for iCCA, highlighting the potential […]