Category: HPB & Spleen

Improved Outcomes with Splenic Artery Embolization in High-Grade Splenic Injuries

Splenic artery embolization (SAE) demonstrates a 72% reduction in in-hospital mortality, shorter ICU length of stay, and lower transfusion requirements compared to splenectomy for hemodynamically stable adult trauma patients with high-grade blunt splenic injuries (Grade ≥ IV). SAE is associated with significantly improved outcomes, making it a potentially safer and more effective management approach for […]

Robotic complex hepatectomy reduces perioperative morbidity for hepatocellular carcinoma

Robotic complex hepatectomy (RCH) offers advantages over laparoscopic complex hepatectomy (LCH) for patients with solitary hepatocellular carcinoma, showing lower blood loss, transfusion rates, and postoperative complications, including 30-day morbidity and post-hepatectomy liver failure. Additionally, RCH is an independent protective factor for reducing major morbidity. These findings suggest that RCH may be a preferable choice for […]

Improved Prediction Models for Recurrence in Unresectable HCC Patients

Novel nomograms utilizing multimodal imaging features and clinical data were developed and validated for predicting disease-free survival after TACE-based downstaging therapy followed by surgical resection in unresectable HCC patients. The nomograms outperformed five major staging systems in risk stratification, offering more accurate prognostic information to guide individualized treatment strategies for patients at high risk of […]

Novel Predictive Model for Colorectal Cancer Liver Metastasis

Primary tumor location, lymph node metastasis, and abnormal tumor markers, along with PD-L1 CPS, were identified as key risk factors for colorectal cancer liver metastasis. A predictive model integrating these factors demonstrated strong accuracy in prognosis, with a determined CPS threshold of 4.5. The model offers valuable clinical guidance for assessing and managing colorectal cancer […]

Long-Term Analysis of Robotic Hepatectomies

First U.S. study on 530 robotic hepatectomies spanning a decade reveals favorable outcomes, including high R0 resection rate, low complication rates, and promising oncological survival rates for various hepatic malignancies. The robotic approach proves safe and effective for liver resections, with a significant number of major procedures performed successfully. Overall, the results highlight the utility […]

Improved Survival with CRS + HIPEC in HCC-PM Patients

CRS + HIPEC provides significant benefits to HCC-PM patients, with 89.0% 1-year and 3-year OS rates. Some patients achieved prolonged PFS, enhancing treatment options for this challenging condition. Incorporating CRS + HIPEC into the treatment regimen is a strategic therapeutic choice for HCC-PM patients, supported by the study’s findings of extended survival outcomes. Journal Article […]

Predicting Biliary Complications in Liver Transplant Patients

Utilizing LASSO logistic regression, researchers identified key risk factors for biliary complications in end-stage hepatic alveolar echinococcosis patients post ex vivo liver resection and autotransplantation. A prognostic nomogram model incorporating age, bile duct dilation, portal hypertension, and resection segments showed good discrimination and accuracy. The model predicted biliary complications with an AUC of 0.818 and […]

Preoperative ICG-R15 Testing Predicts Post-hepatectomy Liver Failure

Preoperative ICG-R15 testing effectively predicts post-hepatectomy liver failure (PHLF) following major liver resection. A retrospective review of 72 patients revealed that 38.9% experienced PHLF, with 33.3% being severity score B and 4.16% score C. Univariate and multivariate analyses identified future liver remnant, ICG-R15 levels, and blood transfusion as independent predictors of PHLF. These findings emphasize […]

Intraoperative Hemodynamic Monitoring for Pancreatectomy

Advanced intraoperative hemodynamic monitoring combined with a clinical decision-making algorithm improved hemodynamic parameters during pancreatectomy, showing a 33.3% reduction in intraoperative hypotension, 31.6% increase in cardiac index, and 37.6% increase in stroke volume variation. Further investigation in larger studies is warranted to validate these findings. Journal Article by Galouzis N, Khawam M (…) Dull RO […]

Income Changes and Pancreatic Cancer Resection

Income changes do not significantly impact the rate of patients undergoing surgical resection for early-stage pancreatic cancer. A study including 23,968 patients from 173 counties across 11 states showcases an overall resection rate of 45.1%, which increased from 42.8% to 47.4% between the early and late time periods. Notably, disparities in surgical intervention between lower-income […]