Ann Surg Oncol1 May 2024
Lymph node metastasis (LNM) in nonfunctional pancreatic neuroendocrine tumors (NF-PNET) has a negative impact on disease-free survival (DFS) and overall survival (OS). In a systematic review of 52 studies involving 24,608 PNET cases, reported LNM rates for NF-PNET ranged from 7% to 64%, with higher…
Ann Surg Oncol1 May 2024
Patients with pancreatic ductal adenocarcinoma (PDAC) and normal levels of CA19-9 and DUPAN-2 are more likely to have resectable and early-stage cancer. In a study of 521 patients, those with normal CA19-9 and DUPAN-2 had a significantly higher proportion of resectable PDAC (71.5%) and a…
Surg Endosc1 May 2024
Survey of 290 pancreatologists revealed significant differences in managing malignant gastric outlet obstruction (MGOO) due to pancreatic cancer. Endoscopic stenting (ES) was most common, but EUS-Gastrojejunostomy (EUS-GJ) adoption is increasing. Decision drivers include life expectancy and patient frailty, with lack of standardized algorithms. Availability of…
HPB & Spleen1 May 2024
Clinicians developed a nomogram to predict cancer-specific survival (CSS) in hepatocellular carcinoma (HCC) patients without lymph node metastasis (LNM), achieving high accuracy in both internal and external validation. Analysis of 6,840 HCC patients revealed age, gender, bone metastasis, lung metastasis, AFP, T stage, surgery, and…
Am Surg1 May 2024
Clinicians found that anchored straight stomach reconstruction (SSR) significantly reduces the incidence of delayed gastric emptying (DGE) after pancreaticoduodenectomy (PD), also leading to improved postoperative nutritional recovery. A case series analysis of 125 PD patients showed that those in the SSR group had a DGE…
Am J Surg30 Apr 2024
Pancreas-preserving duodenectomy (PPrD) achieved an R0 resection rate of 93% among patients treated for duodenal neoplasms. In a retrospective cohort of 29 patients, postoperative complications occurred in 34.4% of cases, with 13.7% at Clavien-Dindo grade III-V. PPrD had lower rates of pancreatic leak, delayed gastric…
HPB & Spleen30 Apr 2024
General surgery is a highly litigious specialty, with most claims related to delays in diagnosis or surgical negligence. A study analyzing malpractice cases from the last two decades found that the majority named surgeons as defendants, with a higher likelihood of verdicts favoring defendants. Payouts…
HPB & Spleen29 Apr 2024
Developed to minimize visible scars on the abdomen, the hidden port site incision technique at the pubic hairline offers a cosmetically superior approach for common foregut and hepatopancreatobiliary procedures. This technique maximizes cosmetic outcomes while maintaining clinical efficacy, especially beneficial for patients with poor healing…
BMC Med29 Apr 2024
External radiotherapy plus camrelizumab as first-line therapy for unresectable intrahepatic cholangiocarcinoma demonstrated a 1-year progression-free survival rate of 44.4% and antitumor activity with low toxicity levels. The objective response rate was 61.1% and the disease control rate was 86.1%. Further investigation is warranted for this…
J Gastrointest Surg29 Apr 2024
A decade-long analysis of 500 robotic hepatectomies reveals the learning curve to achieve long-term mastery. Cumulative sum chart analysis identified a significant minimum number of cases required to overcome the learning curve for minor, major, and technically challenging minor resections. This data can guide surgeons…