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HPB & Spleen9 Feb 2024

Advanced Surgical Treatment of Pancreatic Ductal Adenocarcinoma: Current Challenges and Opportunities

Recent advancements in chemo/radiotherapy have rendered previously inoperable patients with pancreatic ductal adenocarcinoma (PDAC) potentially resectable. This narrative review highlights the current state of surgical treatment for borderline resectable, locally advanced, and synchronous or metachronous oligometastatic PDAC. Neoadjuvant therapy (NAT) is recommended before surgery, although…

Gut8 Feb 2024

Individualized Age Cessation in IPMN Surveillance: A Cost-Effectiveness Analysis

Researchers conducted a simulation study to determine the optimal age to discontinue long-term surveillance of low-risk intraductal papillary mucinous neoplasms (IPMNs). Using a markov model and clinical cohort data, they calculated the cost-effectiveness of continued versus discontinued surveillance at different ages. They found that the…

Ann Surg Oncol8 Feb 2024

Indocyanine Green-Guided Laparoscopic RLPS: Safe and Feasible for Synchronous Liver Metastases

Laparoscopic right posterior sectionectomy (RLPS) with an extrahepatic Glissonian approach and modified hanging maneuver, guided by indocyanine green fluorescence imaging, proves safe and feasible for a patient with mid-rectum adenocarcinoma and synchronous liver metastases. The procedure involves selective clamping, indocyanine green injection, and precise parenchymal…

Ann Surg Oncol8 Feb 2024

Laparoscopic Portal Vein Ligation and Embolization Facilitate Safe Second Hepatectomy for Unresectable Colorectal Liver Metastases

Laparoscopic two-stage hepatectomy with portal vein embolization ensures safe completion of surgery for initially unresectable colorectal liver metastases. Three patients received chemotherapy followed by laparoscopic colorectal resection and limited hepatectomies. After right portal vein ligation, laparoscopic portal vein embolization using ethanol facilitated the second hepatectomy.…

Ann Surg Oncol8 Feb 2024

Adjuvant Therapy Trends Post Resection in Pancreatic Cancer

Approximately 25.2% of pancreatic cancer patients who underwent upfront resection did not receive adjuvant therapy (AT), according to a prospective observational study. The main reasons for AT omission were postoperative complications, oncologist's choice, baseline comorbidities, patient's choice, and early recurrence. Older age, comorbidities, and postoperative…

Appendix, Gallbladder and Surgical Emergencies6 Feb 2024

Implications of precursor lesions and early cancerous changes in the gallbladder and bile ducts

The study explores terminology, classification, and significance of dysplasia and early carcinoma in the gallbladder and bile ducts. Most precursor lesions and early cancerous changes are clinically undetectable. Low-grade dysplasia is challenging to define and lacks clinical significance, but additional sampling is required to exclude…

Ann Surg Oncol5 Feb 2024

Video-Based Indocyanine Green Fluorescence Enables Safe and Effective Robotic Duodenum-Preserving Pancreatic Head Resection

Robotic duodenum-preserving pancreatic head resection (DPPHR) utilizing video-based indocyanine green fluorescence imaging was successfully performed on a 48-year-old patient with pancreatic duct stones and chronic pancreatitis. The surgery lasted 265 minutes with minimal blood loss. Postoperative pathology confirmed the diagnoses, and the patient was discharged…