HPB & Spleen9 Feb 2024
Recent advancements in chemo/radiotherapy have rendered previously inoperable patients with pancreatic ductal adenocarcinoma (PDAC) potentially resectable. This narrative review highlights the current state of surgical treatment for borderline resectable, locally advanced, and synchronous or metachronous oligometastatic PDAC. Neoadjuvant therapy (NAT) is recommended before surgery, although…
Gut8 Feb 2024
Researchers conducted a simulation study to determine the optimal age to discontinue long-term surveillance of low-risk intraductal papillary mucinous neoplasms (IPMNs). Using a markov model and clinical cohort data, they calculated the cost-effectiveness of continued versus discontinued surveillance at different ages. They found that the…
Ann Surg Oncol8 Feb 2024
Laparoscopic right posterior sectionectomy (RLPS) with an extrahepatic Glissonian approach and modified hanging maneuver, guided by indocyanine green fluorescence imaging, proves safe and feasible for a patient with mid-rectum adenocarcinoma and synchronous liver metastases. The procedure involves selective clamping, indocyanine green injection, and precise parenchymal…
Ann Surg Oncol8 Feb 2024
Laparoscopic two-stage hepatectomy with portal vein embolization ensures safe completion of surgery for initially unresectable colorectal liver metastases. Three patients received chemotherapy followed by laparoscopic colorectal resection and limited hepatectomies. After right portal vein ligation, laparoscopic portal vein embolization using ethanol facilitated the second hepatectomy.…
Ann Surg Oncol8 Feb 2024
Approximately 25.2% of pancreatic cancer patients who underwent upfront resection did not receive adjuvant therapy (AT), according to a prospective observational study. The main reasons for AT omission were postoperative complications, oncologist's choice, baseline comorbidities, patient's choice, and early recurrence. Older age, comorbidities, and postoperative…
Ann Surg Oncol7 Feb 2024
This study retrospectively analyzed consecutive patients who underwent surgery for hilar obstruction and aimed to determine factors distinguishing benign from malignant causes and long-term outcomes after resection. Among 182 patients, 14% had benign disease. Significant differences were found in ca19-9 levels and cross-sectional imaging features…
Ann Surg Oncol6 Feb 2024
A 66-year-old male with stage II intrahepatic cholangiocarcinoma underwent a 240-minute laparoscopic left hepatectomy using a no-touch en bloc technique and lymphadenectomy skeletonization. The patient was discharged after 6 days without complications and received postoperative gemcitabine and cisplatin treatment. After 14 months of follow-up, there…
Eur J Surg Oncol6 Feb 2024
Findings from a nationwide analysis revealed that achieving a modified textbook outcome (MTO) after surgery for colorectal liver metastases (CRLM) was associated with better overall survival (OS). Out of 6,525 eligible patients, 81% achieved MTO. Between 2014 and 2018, patients achieving MTO had a 5-year…
Appendix, Gallbladder and Surgical Emergencies6 Feb 2024
The study explores terminology, classification, and significance of dysplasia and early carcinoma in the gallbladder and bile ducts. Most precursor lesions and early cancerous changes are clinically undetectable. Low-grade dysplasia is challenging to define and lacks clinical significance, but additional sampling is required to exclude…
Ann Surg Oncol5 Feb 2024
Robotic duodenum-preserving pancreatic head resection (DPPHR) utilizing video-based indocyanine green fluorescence imaging was successfully performed on a 48-year-old patient with pancreatic duct stones and chronic pancreatitis. The surgery lasted 265 minutes with minimal blood loss. Postoperative pathology confirmed the diagnoses, and the patient was discharged…