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Elderly patients diagnosed with pancreatic adenocarcinoma are more likely to have had a recent cholecystectomy compared to those without. The rate of cholecystectomy in the year prior to cancer diagnosis was 1.9% for the cancer group, significantly higher than the 0.4% observed in the non-cancer…
The long-term results of a phase II trial evaluating neoadjuvant gemcitabine, nab-paclitaxel, and S1 treatment in borderline resectable pancreatic cancer with arterial contact (BRPC-A) show promising outcomes. Of the 47 patients, 96% underwent pancreatectomy, and the updated median overall survival was 41.0 months with 2-…
Recurrence rates of ampullary adenomas (AA) after endoscopic papillectomy (EP) were compared between patients with familial adenomatous polyposis (FAP) and sporadic AA. The study included 257 patients from 10 tertiary hospitals. Recurrence occurred in 48% of patients with FAP and 36.9% of patients with sporadic…
Robotic limited liver resections (RLLR) resulted in superior perioperative outcomes compared to laparoscopic limited liver resections (LLLR) for posterosuperior liver segments, including reduced open conversion rate, blood loss, and operative time. These benefits were observed in both the overall population and in patients with cirrhosis.…
Multiagent neoadjuvant chemotherapy (NAC) followed by surgery is associated with improved overall survival compared to upfront surgery or single-agent NAC in patients with resectable pancreatic adenocarcinoma. A nationwide study conducted on 5,216 patients found that multiagent NAC led to longer median overall survival (35.8 months)…
This systematic review and meta-analysis of 285 studies, including over 8 million patients, evaluated the procedure-specific risks of symptomatic venous thromboembolism (VTE) and major bleeding in general abdominal, colorectal, upper gastrointestinal, and hepatopancreatobiliary surgeries. The risk of VTE varied widely among procedures, with VTE rates…
Metabolic surgery has been found to facilitate the resolution of nonalcoholic steatohepatitis (NASH) and improve fibrosis in patients with obesity. A study comparing the histologic outcomes of metabolic surgery versus nonsurgical care in individuals with fibrotic NASH revealed that half of the surgical patients achieved…
A nationwide audit-based study was conducted to evaluate the long-term uptake and outcomes of minimally invasive distal pancreatectomy (MIDP) following a training program and randomized trial. The study found that the implementation of MIDP increased from 48.6% to 63.0% over time, with a significant variation…
Researchers conducted an international multicenter cohort study to compare outcomes after distal pancreatectomy with or without splenectomy for intraductal papillary mucinous neoplasm (IPMN). They found that patients without preoperative suspicion of malignancy who underwent spleen-preserving distal pancreatectomy had improved short-term outcomes and no significant difference…
Researchers conducted a multicentre randomised controlled trial to explore the impact of the level of pancreatic transection in laparoscopic pancreaticoduodenectomy. The trial compared extended pancreatic neck transection with conventional pancreatic neck transection. The results showed that extended pancreatic neck transection significantly reduced the incidence of…
