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A retrospective cohort study investigated the use of serum carcinoembryonic antigen (CEA) as an alternative prognostic marker for overall survival in patients with localized pancreatic adenocarcinoma and non-elevated levels of carbohydrate antigen 19-9 (CA19-9). The study found that elevated CEA at baseline was independently associated…
The study explored the feasibility of S-1 adjuvant chemotherapy after major hepatectomy for biliary tract cancers. Comparing major hepatectomy (mh) with non-major hepatectomy (nmh), researchers found that mh had a lower treatment completion proportion and dose intensity. Additionally, caution should be exercised to prevent biliary…
Researchers conducted a retrospective analysis to identify risk factors for gallbladder adenoma, a precancerous lesion. They analyzed data from patients who underwent cholecystectomy and found that age, gallbladder wall thickness, polyp size, echogenicity, pedunculation, and adenosine deaminase (ada) levels were independent predictors of gallbladder adenoma.…
The results of a comparative study using a propensity score between right portal vein ligation (RPVL) and embolization (RPVE) for bilobar liver metastases from colorectal cancer show that RPVL and RPVE are both effective in providing left hemi-liver hypertrophy before right hepatectomy. There was no…
A randomized controlled trial assessed the efficacy of rectal indomethacin in preventing post-operative hyperamylasemia (POH) following pancreatoduodenectomy (PD). The study included 44 patients who either received 100mg of indomethacin per-rectally or standard care. The intervention arm had a significantly lower incidence of POH (28.6% vs.…
This study aimed to assess the prevalence of somatic symptom severity (sss), depression, and anxiety in surgical inpatients with different diagnostic groups of abdominal pain. The results showed that somatic symptoms were common, with 52% having moderate and 19.6% having severe sss. There was a…
Ultra-low-pass whole-genome sequencing (ULP-WGS) of circulating tumor DNA (ctDNA) can provide clinically relevant information about tumor biology in patients with hepatocellular carcinoma (HCC) under systemic treatment. The presence of ctDNA and the loss of specific genomic regions (5q and 16q) were identified as independent predictors…
With a higher mortality rate compared to other cancers, pancreatic cancer poses significant challenges. However, there have been improvements in survival rates, although at a slower pace. Researchers have investigated multimodal treatment approaches involving chemotherapy, surgery, and radiotherapy. Recent advancements in treatment regimens show promise…
The study investigated the impact of endoscopic ultrasound (EUS) in the liver transplantation (LT) work-up for patients with unresectable perihilar cholangiocarcinoma (PCCA). EUS screenings were performed on a selected group of patients, and the primary outcome was the number of patients precluded from further screening…
The systematic review and meta-analysis of studies investigating the association of surgical technique with outcomes for colorectal liver metastases (crlm) found that anatomic resection (AR) was associated with improved liver-specific disease-free survival (DFS) and overall DFS in patients with mutras tumors. Specifically, AR resulted in…
