BMC Surg7 Jan 2024
The course of the segment 4 hepatic artery affects the proximal ductal margin status in right hepatectomy for perihilar cholangiocarcinoma. The study found that the l-up type of the artery, running along the left cranial position of the umbilical portion of the left portal vein,…
BMC Surg7 Jan 2024
A meta-analysis of six comparative studies involving 6,874 patients with resected stage I pancreatic cancer revealed that adjuvant chemotherapy is associated with significantly higher overall survival and 2-year survival rates compared to surgery alone. However, there was no statistically significant difference in 1-year, 3-year, or…
BMJ Open6 Jan 2024
The study evaluated the utilization and outcomes of endoscopic retrograde cholangiopancreatography (ERCP) procedures in the first advanced endoscopy center in Palestine. A total of 1909 procedures on 1303 patients were included, with an overall complication rate of 5%. The primary adverse events were post-ERCP pancreatitis…
J Clin Gastroenterol6 Jan 2024
The study analyzed trends in hospitalizations for hepatocellular carcinoma (HCC) in the United States between 2011 and 2017. The researchers found an increase in HCC-related admissions over the years, with a decrease in inpatient mortality rates. However, there was a significant rise in the financial…
Ann Surg Oncol5 Jan 2024
Patients with pancreatic adenocarcinoma who undergo distal pancreatectomy and receive neoadjuvant chemotherapy (NAT) are 73% more likely to develop postoperative deep venous thrombosis (DVT) compared to those who undergo upfront resection. This association is significant and highlights the need to prioritize high-risk patients for extended…
Ann Surg Oncol5 Jan 2024
Patients with mutras colorectal liver metastases (crlm) may benefit from anatomic resection (AR) compared to nonanatomic resection (NAR), according to a systematic review and meta-analysis. The study found that AR was associated with a significant improvement in liver-specific disease-free survival and overall disease-free survival among…
Ann Surg Oncol5 Jan 2024
The study demonstrates that delta radiomic features (DRFs), when combined with clinical variables, are effective in predicting resection margin status (RMS) and overall survival (OS) in neoadjuvant-treated pancreatic cancer patients. The models outperform clinical feature-based and other radiomics feature-based models in predicting OS, disease-free survival…
Ann Surg Oncol5 Jan 2024
Patients with pancreatic cancer who experience cholangitis have reduced overall survival (OS) and progression-free survival (PFS). Interrupting neoadjuvant chemotherapy (NAT) also decreases OS and PFS. Biliary decompression with metallic stents reduces the rate of chemotherapy interruptions and cholangitis compared to plastic stents. However, the choice…
Br J Surg4 Jan 2024
The study aimed to compare the accuracy of prediction models in detecting clinically relevant post-hepatectomy liver failure (PHLF) following major hepatectomy. The researchers evaluated the use of arterial lactate measurements as an early predictor of PHLF in a subgroup of major hepatectomies, finding that lactate…
Ann Surg Oncol4 Jan 2024
A study evaluated whether local therapy benefits patients who experience early recurrence after hepatectomy for colorectal liver metastases (CLM). Clinicopathologic data of 671 patients were analyzed, with 81% experiencing recurrence. Local therapy, including ablation, resection, or radiation, resulted in improved survival for patients with early,…