Multimodal treatment disparities in pancreatic cancer significantly affect patient survival and care. 8,466 patients analyzed; nonmetastatic cases had higher therapy rates than metastatic. Non-Hispanic black patients experienced longer delays to treatment compared to non-Hispanic whites. Uninsured and Medicaid patients showed the highest odds of not receiving therapy in metastatic cases. Primary resection strongly predicts improved […]

Pre-operative shear wave elastography can effectively predict the risk of post-operative pancreatic fistula (POPF) after partial pancreatectomy, impacting surgical decision-making. In a study of 305 patients, lower elastography measurements correlated with a higher risk of POPF. An integrated prediction model using elastography, BMI, and pancreatic duct dilation accurately assessed POPF risk with AUC values over […]

Preoperative conversion therapy significantly enhances surgical outcomes for intermediate-stage hepatocellular carcinoma. 23.2% of patients in the conversion resection group achieved a complete pathological response. Microvascular invasion rates were lower in the conversion group (17.9% vs. 58.6% in direct resection). Consider conversion therapy to improve pathology and survival before resection in select patients. 51.8% of the […]

Tumor markers may improve patient selection for liver resection in HCC. In a study of 803 patients, 32.3% of resectable tumors had high tumor markers (AFP > 500 ng/ml or DCP > 1000 mau/ml). TM-high patients had a median survival of 120.7 months, significantly lower than non-TM-high patients at 160.8 months (p = 0.008). Incorporating […]

A novel risk model using stress granule-related gene signatures (sgrgs) shows promise for improving prognostic accuracy in pancreatic ductal adenocarcinoma (PDAC). Four key sgrgs (lama3, itga6, col17a1, top2a) were identified as significant predictors of PDAC prognosis. A nomogram combining age, N stage, and risk score demonstrated strong predictive capacity. Understanding these markers can enhance patient […]

Robotic hepatectomy enhances surgical options for high-risk liver cancer patients with comparable oncologic outcomes to laparoscopic methods. Robotic techniques show similar length of hospital stay and complication rates to laparoscopic approaches but may offer better precision. Patients experience shorter recovery times and can start adjuvant therapy sooner. Surgeons should consider robotic hepatectomy as a viable […]

Identifying effective strategies for preventing postoperative pancreatic fistula (POPF) can significantly impact patient outcomes after pancreatoduodenectomy (PD). Overall POPF rate was 15.1%; drains alone showed no association with POPF. For moderate fistula risk score patients, drains alone reduced POPF from 19.8% to 13.1%. High-risk patients benefited most from a drain combined with a stent, lowering […]

A new CT-based online calculator predicts survival benefits from adjuvant transarterial chemoembolization after surgical resection in hepatocellular carcinoma patients. 35.4% of patients evaluated may benefit from pa-tace, increasing 5-year overall survival probability by 19.4% and adding 22.5 months of restricted mean survival time. The tool outperforms traditional staging systems with a c-index of 0.694 and […]