Robotic-assisted pancreatic surgery significantly reduces complications and improves recovery compared to laparoscopic methods. Conversion rates were lower in robotic cases (2.5% vs. 17.2%, p < 0.001). Blood loss was less with robotic surgery (119 ml vs. 179 ml, p = 0.013), and recovery time was faster (8.2 days vs. 9.6 days, p = 0.038). Robotic […]
Category: HPB & Spleen
New lymph node thresholds increase survival in pancreatic cancer
In intraductal papillary mucinous neoplasm-derived pancreatic cancer, removing at least 20 lymph nodes dramatically improves survival outcomes. The minimum required for accurate staging is 10 lymph nodes (p=0.040). Optimal lymphadenectomy of 20 nodes leads to a median overall survival of 80.3 months compared to 37.2 months with fewer nodes (p<0.001). Prioritizing at least 20 lymph […]
Machine learning stratifies HCC recurrence risk after surgery
A new model predicts recurrence and mortality for hepatocellular carcinoma (HCC) patients post-surgery, enhancing patient management. The Random Survival Forest model identifies high-risk patients, showing a 5-year recurrence rate of 87.3% vs. 51.5% in low-risk patients (training) and 75.9% vs. 64.8% (validation). High-risk patients have a 5-year mortality rate of 56.0% vs. 15.3% (training) and […]
Robotic vs. Laparoscopic Liver Resection: Insights on Depth Impact
Robotic liver resection offers advantages over laparoscopic approaches, especially with deeper transections. In deeper liver transections (>2.5 cm), robotic resection had a significantly shorter operative time (145 mins vs. 231 mins, p<0.001). Blood loss was less in robotic cases (nil vs. 100 ml, p=0.006) and led to better overall outcomes, with 76.7% achieving textbook results […]
Understanding Incidental Gallbladder Cancer Risks and Treatments
Identifying residual disease in incidental gallbladder cancer is crucial for improving surgical outcomes. Residual disease was found in 36% of patients, significantly lowering recurrence-free survival (42 months vs. 11 months) and overall survival (60 months vs. 22 months). Key risk factors for residual disease include CA19-9 levels >39 U/ml, open cholecystectomy, and advanced tumor stages. […]
Liver resection improves survival for advanced HCC with invasion
Liver resection combined with systemic therapy offers better survival for patients with hepatocellular carcinoma and macrovascular invasion. Overall survival rates at 1, 3, and 5 years post-resection were 65.9%, 37.7%, and 28.6%, vastly superior to 29.3%, 10.1%, and 5.4% in non-resection groups. Preoperative systemic therapy led to even higher survival rates: 81.2%, 50.0%, and 40.6% […]
PAXG Outperforms mFOLFIRINOX in Resectable Pancreatic Cancer
PAXG shows superior efficacy over mFOLFIRINOX for patients with resectable pancreatic ductal adenocarcinoma. Median event-free survival (EFS) for PAXG is 16.0 months compared to 10.2 months for mFOLFIRINOX. EFS hazard ratio is 0.63, indicating a significant benefit for PAXG (p=0.0018). Surgeons should consider PAXG as the preferred preoperative chemotherapy regimen for this patient population. Adverse […]
Minimally Invasive Approaches Outperform Open Liver Resection
Robotic-assisted and laparoscopic liver resection yield better outcomes for BCLC stage 0/A hepatocellular carcinoma compared to open surgery. Operative times were longer for robotic (225 min) and laparoscopic (225 min) than for open (170 min, p < 0.001). Postoperative complications were lower for robotic (12.5%) and laparoscopic (13.4%) versus open (17.1%, p < 0.001), with […]
New Prognostic Model for Unresectable Liver Cancer Treatment
This study develops and validates a prognostic model for patients with unresectable hepatocellular carcinoma treated with transcatheter arterial chemoembolization plus lenvatinib. Identified nine key risk factors impacting overall and progression-free survival, including tumor number and extrahepatic metastases. Survival prediction model showed area under the curve values of 0.706 at 3 years for overall survival and […]
Nutritional Status Critical for Pancreatic Surgery Outcomes
Evaluating nutrition and body composition can enhance post-surgery success in pancreaticoduodenectomy. 57.2% of patients achieved a textbook outcome, with no 30-day mortality. Key risk factors for not achieving a textbook outcome include age ≥75, malnutrition, and a high visceral fat to muscle ratio. Focusing on these factors preoperatively may significantly improve patient outcomes and overall […]
