Category: HPB & Spleen

Liver Venous Deprivation Outperforms Portal Vein Embolization for Liver Cancer

Liver venous deprivation (LVD) enhances outcomes versus portal vein embolization (PVE) among liver cancer patients needing preoperative liver augmentation. LVD significantly boosts future liver remnant growth by 24.57% and daily volume by 4.30%. It shortens surgery wait times by over 5 days and operation duration by nearly 43 minutes. Resection completion rates improve by 73%, […]

Adherence to BCLC Guidelines Boosts Survival in HCC

Real-world adherence to BCLC treatment guidelines in hepatocellular carcinoma significantly impacts patient survival. Overall adherence was only 47.8%, with the best rates (93.5%) in stage D and the lowest (23.1%) in stage C. Patients following BCLC recommendations lived longer: 722 days versus 535 days for non-adherents. Improving adherence, especially in early and advanced stages, is […]

Multifocal Cholangiocarcinoma: Rethinking Prognosis

Surgeons need to reconsider the staging of multifocal intrahepatic cholangiocarcinoma as all cases should be classified as AJCC stage III, impacting surgical decision-making. Patients with multifocal tumors showed worse overall survival (26.1 vs. 60.0 months) and disease-free survival (9.8 vs. 25.0 months) compared to solitary tumors of stage II. Genomic profiling revealed that both satellite […]

Improved Liver Segmentation Enhances Surgical Planning

Surgeons can refine liver surgery strategies with a new patient-specific segmentation method focused on vascular structures. This new hepatic and portal vein-based classification (hpvc) showed better anatomical alignment than conventional methods, particularly for complex liver segments 5 and 8. Surgeons rated hpvc higher in accuracy for surgical planning and anatomical adherence compared to traditional classifications […]

Mastering Robotic Liver Resection: Frequency Matters

Frequent access to robotic platforms leads to better outcomes in liver resection. Conversion rate was 10.8%, with significant variance in blood loss based on imm grade: 184 ml (grade 1), 381 ml (grade 2), 753 ml (grade 3). Competency was achieved faster by surgeons with high-frequency access (35 cases vs. 47 cases). Structured training and […]

Anatomical Resection Cuts Early Recurrence in HCC Patients

Anatomical resection can significantly reduce early recurrence rates in select hepatocellular carcinoma patients. In patients with tumors ≤5 cm and non-smooth margins, anatomical resection led to a 16.76% absolute reduction in early recurrence risk. Patients with these characteristics showed improved recurrence-free survival compared to non-anatomical resection. Identifying patients with specific radiological features can optimize surgical […]

Innovative Two-Stage Hepatectomy for Intrahepatic Cholangiocarcinoma

Surgeons can safely resect complex liver tumors using a novel two-stage approach that minimizes ischemic injury. Combining total vascular exclusion with veno-venous ECMO and hypothermic perfusion led to negative margins in a patient with unresectable intrahepatic cholangiocarcinoma. Operative time was 4 hours and 3 minutes, with 72 minutes of hypothermic perfusion and 130 minutes of […]

Fewer Endocrine Complications with Completion Pancreatectomy

Completion pancreatectomy reduces severe endocrine complications compared to total pancreatectomy. Total pancreatectomy patients face a 2.9-fold increase in endocrine issues during the first year post-surgery. Risk of hypoglycemia is 3.0 times higher, while diabetic ketoacidosis risk is 9.3 times greater in total pancreatectomy patients. Surgeons should consider completion pancreatectomy for better endocrine outcomes and enhance […]

Effective Nonsurgical Strategy for Benign Biliary Strictures

Magnetic compression anastomosis offers a promising option for patients with completely obstructed benign biliary strictures unresponsive to standard therapies. 92.9% overall success rate in 113 patients treated with MCA. Only 14.3% experienced recurrence, with a median of 23.7 months after treatment. Surgeons can consider MCA as a viable alternative, minimizing the need for surgical interventions. […]

Endoscopic Ultrasound Outperforms PTBD for Biliary Obstruction

Endoscopic ultrasound (EUS) is a cost-effective strategy for managing malignant distal biliary obstruction (MDBO) after failed ERCP, leading to better outcomes. EUS-guided biliary drainage (EUS-GB) cost $14,520, yielding 0.38 QALYs and an incremental net monetary benefit (NMB) of $37,768. EUS-guided choledochoduodenostomy (EUS-CBD) cost $17,694, providing 0.55 QALYs and an incremental NMB of $52,171. EUS techniques […]