A comparative analysis of surgical approaches for extrahepatic cholangiocarcinoma revealed that hemihepatectomy (HH) had fewer severe complications, lower pancreatic fistula rates, and shorter hospital stays than pancreatoduodenectomy (PD). However, HH showed a higher perioperative mortality rate among right hemihepatectomy patients. At one year post-surgery, patients undergoing HH maintained better skeletal muscle area, body fat, and […]
Category: HPB & Spleen
Intrahepatic and perihepatic abscesses significantly affect postoperative outcomes.
A multicenter study found that 3.3% of 4621 hepatocellular carcinoma patients developed intrahepatic and perihepatic abscesses (ipha) post-hepatectomy. These abscesses led to longer hospital stays (16 vs. 11 days), increased 30-day readmission rates (33% vs. 3.1%), and higher 90-day mortality (11.7% vs. 2.8%). Key risk factors included obesity, diabetes, and major surgical procedures. A novel […]
Laparoscopic pancreatoduodenectomy shows improved outcomes compared to open surgery
A network meta-analysis of seven randomized controlled trials involving 1,336 patients revealed that laparoscopic pancreatoduodenectomy (LPD) offers shorter hospital stays and reduced intraoperative blood loss compared to open pancreatoduodenectomy (OPD). However, LPD was associated with longer operative durations. In contrast, robotic pancreatoduodenectomy (RPD) showed no significant advantages over OPD. While LPD indicated potential better outcomes, […]
Perihilar resection increases risk of biliary leakage post-surgery
In a study analyzing data from 724 patients undergoing biliary anastomosis, researchers reported a 5.6% bile leak rate in distal malignant obstruction cases, while the rate increased to 14.6% in proximal malignant cases. Mortality varied significantly between anastomotic failure (26%) and no failure (2.6%). Advanced comorbidities and elevated preoperative bilirubin levels correlated with higher leak […]
Muscle mass-to-fat ratio predicts outcomes in pancreatic cancer surgery
A study evaluating the muscle mass-to-fat ratio (mmfr) in pancreatic cancer patients revealed significant prognostic implications. Among 191 patients undergoing pancreaticoduodenectomy, those in the low-mmfr group faced shorter overall survival and higher incidences of postoperative pancreatic fistula compared to their high-mmfr counterparts. The optimal mmfr cutoff values were identified at 0.688 for males and 0.382 […]
Robotic pancreaticoduodenectomy shows promising safety and feasibility
Analysis of 425 patients in Japan demonstrates that robotic pancreaticoduodenectomy (RPD) can be safely introduced, achieving a low conversion rate to open surgery (3.8%) and high minimally invasive surgery completion rate (91.1%). The median operative time was 617 minutes, with a median blood loss of 160 grams. While the complication rate was 20.5%, mortality rates […]
Deep-learning model surpasses traditional methods in predicting HCC recurrence
A novel deep-learning model, Recurr-Net, showed superior accuracy in predicting hepatocellular carcinoma (HCC) recurrence post-surgery compared to histological microvascular invasion (MVI) and conventional clinical prediction scores. In a study of 1,231 patients, Recurr-Net achieved AUROC scores between 0.770 and 0.857 for internal validation, significantly better than MVI and various clinical risk scores. The model effectively […]
Delayed gastrointestinal recovery affects 16% of hepatectomy patients
The study found that 16% of patients experienced delayed return of gastrointestinal function (DRGF) after partial hepatectomy, which was notably linked to major surgery, longer operation times, and postoperative complications like biliary leaks. Among the 82 affected patients, some required a second nasogastric tube placement, and they also experienced increased risks of pneumonia and lengthened […]
Splenectomy linked to shorter survival in pancreatic cancer patients
A nationwide analysis of pancreatic cancer patients reveals that those who underwent total pancreatectomy with a spleen-preserving approach exhibited significantly prolonged survival (17.3 months) compared to those who had splenectomy (9.6 months). The study highlighted splenectomy as an independent risk factor for shorter overall survival, corroborated by a meta-analysis linking the procedure to decreased longevity […]
Augmented Reality and Fluorescence Imaging Enhance Hepatectomy Outcomes
A study examined laparoscopic parenchyma-sparing hepatectomy for colorectal liver metastases, comparing procedures using augmented reality navigation and fluorescence imaging (ARN-FI) versus traditional methods. Findings indicated that the ARN-FI group experienced shorter transection times, reduced postoperative stays, and wider margins, although recurrence-free survival rates did not differ significantly. Notably, for deep-seated tumors, the ARN-FI approach resulted […]
