HPB & Spleen28 Sep 2025
Biliary strictures, often resulting from various causes, disrupt bile flow and lead to significant complications. Traditional surgical methods are now complemented by advanced strategies, including molecular therapies targeting fibrosis pathways, gene-editing technologies, and tissue-engineered scaffolds. These approaches promise improved, safer treatment options tailored for precision…
Surg Endosc27 Sep 2025
Minimally invasive liver surgeries demonstrate significant benefits over open resections, especially in advanced cases. Among 686 patients, robotic-assisted procedures reduced major complications to 8%, compared to 17% for laparoscopic and 23% for open surgeries. Both laparoscopic and robotic approaches showed lower blood loss and shorter…
Updates Surg27 Sep 2025
Implementing the Enhanced Recovery After Surgery (ERAS) protocol significantly enhances perioperative outcomes in robotic hepatectomy. A study of 544 patients revealed reduced estimated blood loss—from 214.7 to 141.7 mL—and a drop in 90-day readmission rates from 22.6% to 13.4%. Notably, post-ERAS patients presented higher rates…
J Gastrointest Oncol26 Sep 2025
Patients with unresectable colorectal cancer and 10+ liver metastases experience notable survival benefits from hepatic resection combined with radiofrequency ablation (RFA) and systemic therapy. Three-year survival rates soar to 39.2% for surgery approaches, compared to just 18.6% and 8.2% for RFA plus systemic therapy and…
HPB & Spleen26 Sep 2025
Percutaneous catheter drainage (PCD) significantly outperformed percutaneous aspiration (PA) in treating liver abscesses. PCD demonstrated higher treatment success rates and led to quicker clinical improvements, reducing recovery time by nearly two days. Additionally, PCD lowered the six-month recurrence rate by 56%. Both methods displayed comparable…
J Gastrointest Oncol25 Sep 2025
Venous thromboembolism (VTE) affects 15.6% of pancreatic cancer patients, significantly higher than other malignancies. Key risk factors include tumor location in the body or tail, poorly differentiated tumors, stage IV disease, metastasis, and elevated D-dimer levels post-surgery. The study’s findings emphasize the need for early…
J Am Coll Surg24 Sep 2025
Female patients demonstrated significantly better surgical outcomes following pancreatectomy compared to males, with 62.3% of women achieving ideal outcomes versus 54.1% of men. Women faced fewer complications, lower reoperation rates, and reduced 30-day mortality. The likelihood of achieving optimal results was notably higher for women…
Int J Surg24 Sep 2025
Primary liver cancer (PLC) incidents surged 74% from 2000 to 2021 among adults aged 55+, with deaths rising 67% and disability-adjusted life years (DALYs) increasing 59%. While the annual incidence rates are projected to initially fall, projections indicate continuous case increases through 2050, especially in…
Ann Surg Oncol23 Sep 2025
Hepatic arterial infusion pump (HAIP) chemotherapy delivers targeted therapy directly to the liver, markedly improving survival outcomes in liver-confined colorectal metastases (CRLM) and intrahepatic cholangiocarcinoma (ICCA). In unresectable CRLM, five-year overall survival rates reach 50%. Adjuvant HAIP after tumor resection shows two-year survival of 86%,…
Updates Surg23 Sep 2025
Adjuvant therapy markedly enhances overall survival (OS) and disease-free survival (DFS) in patients post-pancreaticoduodenectomy for distal cholangiocarcinoma. A meta-analysis of 22 studies involving 7,078 patients revealed an OS hazard ratio of 0.80 and a DFS hazard ratio of 0.84 for adjuvant therapy compared to follow-up…