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Ann Surg Oncol29 Sep 2025

New margin classifications reshape treatment strategies for hilar cholangiocarcinoma

A retrospective analysis of 218 patients reveals that refined resection margin classifications significantly impact recurrence patterns in hilar cholangiocarcinoma. Adjuvant radiotherapy sharply reduces local recurrence rates, particularly in patients with narrow-clear and invasive margins. Notably, no recurrences were observed in patients with wide-clear, narrow-clear, or…

Hepatobiliary Pancreat Dis Int29 Sep 2025

Machine Learning Accurately Predicts Recurrence and Death in Liver Cancer Patients

A novel random survival forest model effectively stratifies hepatocellular carcinoma patients into high- and low-risk groups for recurrence and mortality post-surgery. Utilizing critical clinicopathological features and molecular markers, the model demonstrates significant differences in 5-year recurrence and death probabilities. For instance, in the training cohort,…

Appendix, Gallbladder and Surgical Emergencies29 Sep 2025

New Quality Standard for Laparoscopic Stone Removal Improves Surgical Outcomes

A new composite criterion, coined the textbook outcome (TO), evaluates laparoscopic common bile duct exploration for choledocholithiasis. Analyzing 225 patients, 74.2% achieved TO, defined by key perioperative benchmarks such as no residual stones and no severe complications. High ASA scores emerged as a critical risk…