Newsletter
Every new paper in this field, in your inbox.
A streamlined approach to pancreatic and hepatocellular cancer treatment in Scotland significantly slashed the time from diagnosis to definitive treatment. Median treatment initiation for hepatocellular carcinoma (HCC) decreased from 98 to 62 days, while for pancreatic cancer (PC) the timeline shortened from 54 to 38…
Surgeons successfully performed an ex vivo liver resection and autotransplantation in a patient with extensive inferior vena cava leiomyosarcoma. The operation included en bloc tumor removal, extensive vascular reconstruction, and involvement of open-heart surgery techniques. After a 13-hour procedure and significant blood loss, the patient…
Minimally invasive distal pancreatectomy (MIDP) markedly reduces hospital stays, infections, and 90-day mortality compared to open distal pancreatectomy (ODP) in pancreatic ductal adenocarcinoma patients. Analyzing data from 20 studies involving 9,339 patients, MIDP also leads to significantly lower blood loss and transfusions. Despite showing better…
A new patch reconstruction technique for venous resection during pancreatoduodenectomy offers significant advantages. It preserves essential venous collaterals while maintaining oncologic radicality, minimizing risks of torsion or stenosis typically seen with segmental resection. This versatile approach is effective for both open and robotic surgeries, addressing…
Positive lymph node status dramatically increases the risk of very early recurrence—defined as recurrence within three months—after neoadjuvant therapy and curative resection for pancreatic ductal adenocarcinoma. In a cohort of 305 patients, 9.1% experienced this rapid recurrence, which severely impacts overall survival (6 months vs.…
A novel surgical burden score (SBS), factoring in adjusted blood loss and operative time, significantly forecasts postoperative complications in hepatocellular carcinoma (HCC) surgery. Among 801 patients analyzed, complications were noted in 39.1%, with severe cases at 11%. The SBS model surpassed existing models, achieving area…
A newly developed nomogram effectively predicts overall survival for hepatocellular carcinoma (HCC) patients with major vascular invasion. Analyzing data from 2,211 patients, key survival factors include tumor size, N stage, metastases, and treatment modalities. The model demonstrates robust predictive accuracy with c-index values around 0.72–0.73…
New endoscopic methods, EDGE and EDEE, revolutionize access to the biliary system for patients with surgically altered anatomy. These techniques facilitate minimally invasive procedures, significantly lowering morbidity rates while maintaining high success rates. By using lumen-apposing metal stents, they improve safety profiles and expand treatment…
Early drainage with lavage and delayed step-up surgery demonstrate significant survival benefits in necrotizing pancreatitis, decreasing mortality and complications. In contrast, delayed video-assisted surgery leads to higher mortality rates. No significant differences between early and delayed intervention approaches were found. Tailoring treatment based on individual…
Postoperative antibiotic prophylaxis (ppa) significantly lowers the incidence of liver-specific surgical site infections (liver-ssi) in patients undergoing simultaneous liver and colorectal resections. In a cohort of 250 patients, those receiving ppa experienced a liver-ssi rate of 11% versus 29.3% in the control group (p
