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Innovative Ex Vivo Surgery and Autotransplantation Successfully Treats IVC Leiomyosarcoma

Surgeons successfully performed an ex vivo liver resection and autotransplantation in a patient with extensive inferior vena cava leiomyosarcoma. The operation included en bloc tumor removal, extensive vascular reconstruction, and involvement of open-heart surgery techniques. After a 13-hour procedure and significant blood loss, the patient was discharged after a month and remains disease-free 16 months post-surgery. The approach demonstrates promising outcomes for complex cases traditionally fraught with high risks.

Journal Article by Yoshikawa J, Liou P (…) Kato T et 2 al. in Ann Surg Oncol

© 2025. The Author(s).

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