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An international survey reveals that 91.6% of surgeons advocate for preoperative chemotherapy in initially unresectable intrahepatic cholangiocarcinoma (ICCA). Most cite tumor downstaging and selecting favorable cases for R0 resection as major benefits. Key concerns defining unresectability include insufficient future liver remnant volume and inability to…
Patients with very early intrahepatic cholangiocarcinoma (ICC) show significant long-term survival, with 1-, 3-, and 5-year overall survival rates at 92.3%, 72.6%, and 58.0%, respectively. However, elevated carbohydrate antigen 19-9 (CA19-9) levels correlate with worse overall and recurrence-free survival rates, indicating more aggressive tumor features.…
Surgical resection post-systemic therapy for hepatocellular carcinoma (HCC) yields encouraging long-term outcomes. In a cohort of 96 patients, median overall survival reached four years, with one-year survival rates at 86.1%. R0/R1 resection correlated with improved progression-free and overall survival, presenting a significant therapeutic advantage. Complications…
Laparoscopic ultrasound-guided resection and microwave ablation significantly improve patient outcomes for colorectal liver metastases (CRLM). In a study of 300 patients, the technique effectively reduced complications and enhanced survival when compared to traditional imaging methods. Notably, intraoperative contrast-enhanced ultrasound with Sonazoid emerged as an independent…
Endoscopic ultrasonography (EUS) has transformed from a diagnostic tool to a crucial therapeutic method. Today, EUS-guided procedures are standard for managing symptomatic pancreatic fluid collections and offer alternatives for high-risk surgical patients with acute cholecystitis. It also provides solutions for biliary obstructions after failed ERCP.…
Early progressive resistance exercise after pancreaticoduodenectomy accelerates recovery, significantly reducing time to first water intake, food intake, ambulation, and length of hospital stay. With 80 patients involved, those engaging in structured exercise reported faster functional recovery compared to controls receiving standard care. The findings highlight…
A novel MRI-based scoring model effectively predicts early recurrence of hepatocellular carcinoma (HCC) after surgical resection. Analyzing data from 310 patients, researchers identified tumor number, tumor margin, peritumoral enhancement, and macrovascular invasion as key predictors. With a simple scoring system, the model demonstrated high sensitivity…
Same-day pancreatic multidisciplinary clinics (PMDC) significantly enhance care for metastatic pancreatic cancer patients. This approach increases rates of genetic testing, access to palliative services, and timely treatment initiation. Notably, PMDC patients survived an average of 487 days compared to 267 days for those receiving standard…
A groundbreaking non-water-cooled microwave ablation needle with a double-layer vacuum design significantly reduces carbonization while maintaining ablation efficacy. Experimental results reveal that a long-needle variant forms a carbonization-free solidification zone of 34 mm in 180 seconds, outperforming its short-needle counterpart, which takes 300 seconds for…
In patients undergoing pancreaticoduodenectomy with severe hyperbilirubinemia (≥14.6 mg/dl), preoperative biliary drainage significantly reduces 90-day mortality from 13.3% to lower rates seen in other groups (2.9-5.7%). While biliary drainage increases the risk of surgical site infections (21.2-26.4%), it decreases overall morbidity compared to non-drained patients…
