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HPB & Spleen23 Jun 2025

New strategies identified to prevent complications from ERCP

In the past five years, research highlights advancements in avoiding complications from endoscopic retrograde cholangiopancreatography (ERCP), particularly post-ERCP pancreatitis (PEP). Key findings include identifying pancreatic steatosis as a novel risk factor and employing machine learning models for PEP prediction. Prophylactic measures have expanded to encompass…

BMC Surg22 Jun 2025

Machine-learning model accurately predicts gallbladder polyp malignancy

A novel machine-learning model, particularly the random forest algorithm, distinguishes between benign and malignant gallbladder polyps, utilizing clinical and ultrasound data from 1,050 patients. Key predictive factors identified include polyp size, age, fibrinogen levels, and presence of stones. The model achieved impressive performance metrics with…

BMJ Open22 Jun 2025

Systemic indocyanine green lowers bilirubin levels post-liver surgery

A clinical trial involving 84 liver surgery patients revealed that systemic administration of indocyanine green (ICG) significantly reduced total bilirubin concentration in postoperative drainage fluid, compared to historical controls. On postoperative day three, the intervention group showed a mean difference of -1.11 mg/dl (p

Ann Surg Oncol18 Jun 2025

Future liver remnant optimization improves surgical outcomes.

Enhancing the future liver remnant (FLR) before major hepatectomy significantly boosts patient outcomes, addressing post-operative liver failure risks. Various techniques such as portal vein embolization, ligation, and liver venous deprivation show distinct advantages and limitations for FLR hypertrophy. While comparative studies exist, controlled trials are…

BMC Surg18 Jun 2025

Chen’s pancreaticojejunostomy shows low complication rates in surgery

A recent study evaluated the efficacy of Chen's pancreaticojejunostomy in laparoscopic pancreaticoduodenectomy among 112 patients with soft pancreatic texture and small main pancreatic ducts. The procedure yielded a low postoperative pancreatic fistula rate of 7.1%, all classified as grade B, with no grade C occurrences.…

Ann Surg16 Jun 2025

Global Consensus Established for Managing Perihilar Cholangiocarcinoma

A multidisciplinary jury of 71 international experts produced 71 recommendations for managing perihilar cholangiocarcinoma (pcca) after reviewing 570 studies. Their consensus emphasized the need for centralized care and multidisciplinary expertise to improve patient outcomes, focusing on curative resection and minimizing morbidity. Through a systematic evidence…

BMC Surg16 Jun 2025

Angioembolization use increases but in-hospital mortality remains unchanged

A comprehensive analysis of severe liver injuries revealed a stable in-hospital mortality rate of 18.7% from 2017 to 2022, despite increasing utilization of angioembolization as a treatment strategy. Compared to laparotomy, angioembolization—either alone or combined with other methods—demonstrated improved survival rates. However, observation only led…

Langenbecks Arch Surg16 Jun 2025

New Index Predicts Liver Failure Risk After Hepatectomy

A new preoperative assessment index integrating liver-to-spleen signal intensity ratio of the remnant liver and future liver volume effectively predicts post-hepatectomy liver failure (PHLF). In a study of 333 patients, those with a volume-adjusted ratio below 0.147 were significantly linked to PHLF, with a particularly…

Eur J Surg Oncol15 Jun 2025

Machine learning predicts perineural invasion in cholangiocarcinoma patients

A novel machine learning model effectively predicts perineural invasion (PNI) in intrahepatic cholangiocarcinoma (ICC) patients preoperatively, offering new insights for clinical decision-making. The XGBoost algorithm demonstrated superior predictive performance, highlighting tumor size, number, and lymph node metastasis as key factors. Significant differences were observed in…

BMC Surg14 Jun 2025

Dynamic risk stratification improves identification of high-risk patients

A study analyzing data from 234 pancreatoduodenectomy patients established that dynamic risk stratification using serum pancreatic amylase and other biomarkers can effectively identify those at high risk for clinically relevant postoperative pancreatic fistula (POPF). The findings indicate that serum pancreatic amylase levels on postoperative days…