World J Surg1 Apr 2025
A study analyzing the branching patterns of the right intrahepatic portal vein identified 12 distinct types, emphasizing the anatomical variations of the right anterior and posterior portal veins. Three-dimensional visualization technology was utilized to analyze 711 patients, revealing the cranio-caudal and ventro-dorsal configurations among others.…
Eur J Med Res1 Apr 2025
In a study involving 199 hepatocellular carcinoma patients, the use of adjuvant PD-1 inhibitors significantly improved both recurrence-free survival (RFS) and overall survival (OS) rates. After propensity score matching, 1-year RFS was 87.1% for those receiving PD-1 inhibitors versus 44.6% for non-recipients, while 1-year OS…
Hepatology31 Mar 2025
A large-scale population-based cohort study involving 4,932,211 adults revealed that individuals with metabolic syndrome face a significantly heightened risk of cholangiocarcinoma, with a multivariate-adjusted hazard ratio of 1.20. During 35,879,371 person-years of follow-up, there were 6,117 identified cases, with incidence rates rising in correlation with…
Ann Surg31 Mar 2025
A systematic review involving 12,469 patients indicates that broad-spectrum penicillin-based antibiotics (bs-ab) notably reduce surgical site infections, postoperative pancreatic fistula rates, and mortality compared to standard cephalosporins. Specifically, bs-ab led to a 47% decrease in surgical site infections and a 38% reduction in postoperative pancreatic…
HPB & Spleen30 Mar 2025
Combining contrast-enhanced CT with MRI significantly boosts the detection of colorectal liver metastases, achieving sensitivity rates of 96.5% compared to 90.6% for MRI alone. Specificity also improved, from 95.3% to 98.3%. Notably, radiologists reported higher diagnostic confidence in 78.8% of cases with the combined approach,…
BMC Med29 Mar 2025
A novel prognostic model utilizing pathological signatures effectively predicts postoperative recurrence risk and sorafenib response in hepatocellular carcinoma (HCC) patients. Analyzed across 287 non-treated patients, the model achieved AUROC values of 0.818 and 0.811 for predicting one and two-year recurrence respectively. Validation with an external…
Transplant Proc29 Mar 2025
Transarterial embolization (TAE) demonstrates a 100% hemostasis success rate in treating ruptured hemorrhages and postablation bleeding in liver cancer patients. The 30-day survival rates were 90.91% for the rupture group and 100% for the ablation group, with 1-year survival rates of 45.45% and 85.19%, respectively.…
J Am Coll Surg27 Mar 2025
A comprehensive analysis revealed that opioid reduction strategies initially aimed at pancreatectomy markedly influenced posthepatectomy prescribing. With a cohort of 2,005 patients, researchers documented over a 50% reduction in intraoperative and total inpatient opioid use, coupled with a 73% decline in discharge opioids. Importantly, patient…
Surg Laparosc Endosc Percutan Tech27 Mar 2025
A systematic review and meta-analysis of endoscopic ultrasound-guided pancreatic duct drainage (EUS-PD) revealed significant effectiveness, with technical success at 89% and clinical success at 88%. Examining 27 trials involving 902 patients, the study also noted a 17% rate of adverse events, primarily post-EUS-PD acute pancreatitis…
Eur J Surg Oncol25 Mar 2025
An international multicenter study validated the Iwate difficulty scoring system (DSS) for laparoscopic liver resections (LLR) across both its four difficulty levels and 12-point difficulty index. Analyzing 14,759 patients, researchers found that intraoperative and postoperative outcomes—such as operation time, blood loss, and complications—worsened significantly with…