A novel nomogram has been developed to predict postoperative biliary fistula (PBF) risk after pancreaticoduodenectomy. Analyzing data from 196 patients, researchers identified diabetes, low albumin, postoperative gastroparesis, abdominal bleeding, abdominal infection, and pancreatic fistula as independent risk factors. The model demonstrated good discriminative ability with an AUC of 0.807 in the training set and 0.782 […]
Category: HPB & Spleen
Nomogram effectively predicts severe complications post-surgery after COVID-19
A novel nomogram crafted to forecast severe postoperative complications in elective hepato-pancreato-biliary surgery following COVID-19 breakthrough infections demonstrated high accuracy. The model utilized data from 2,636 patients and identified significant predictors, including timing of surgery relative to the infection and vaccination status. With an area under the curve (AUC) ranging from 0.841 to 0.919 across […]
Laparoscopic hepatectomy shows safety and effectiveness for liver cancer
Laparoscopic hepatectomy (LH) emerges as a safe, effective treatment for primary hepatocellular carcinoma (HCC) in favorable locations, as seen in a study involving 159 patients. While LH and open hepatectomy (OH) showed no significant differences in major complications or 90-day mortality, LH reduced transfusion rates, hospital stays, and readmission rates. Importantly, long-term survival outcomes remained […]
Understanding jejunal vein anatomy improves surgical outcomes in pancreatoduodenectomy
A systematic review and meta-analysis of 14 studies involving 1,888 patients revealed key anatomical insights into jejunal veins during pancreaticoduodenectomy. The findings indicate that 79.6% of cases exhibit a posterior course of the first jejunal vein (FJV) and jejunal trunk (FJT), while 20.4% show an anterior course. Preoperative radiological assessment of these variations potentially enhances […]
Minimally invasive liver resection options show safety for colorectal cancer patients
A systematic review and network meta-analysis involving 13 studies and 6,582 patients examined the effectiveness of open, laparoscopic, and robotic liver resections for colorectal liver metastases. Findings indicated no significant differences in R0 resection rates, disease-free survival, or overall survival among the methods. However, laparoscopic and robotic techniques displayed reduced postoperative complications, with robotic procedures […]
Major morbidity and mortality linked to complications post-surgery
Among 2,186 patients undergoing major liver resection for perihilar cholangiocarcinoma, a failure to rescue (FTR) rate of 24% was identified in those with severe complications. Key factors associated with FTR included age, higher ASA classification, jaundice at presentation, right-sided resections, and low annual hospital surgical volume. Notably, liver failure significantly increased the odds of FTR […]
Magnesium supplementation may help prevent acute pancreatitis.
A systematic review of twelve studies reveals magnesium deficiency in pancreatic acinar cells is often linked to reduced serum calcium, predisposing individuals to acute pancreatitis. The research indicates that magnesium acts as a natural calcium antagonist, mitigating intracellular calcium accumulation and premature enzyme activation. Supplementation shows promising benefits in preventing acute pancreatitis, particularly post-endoscopic retrograde […]
Omitting Abdominal Drains Reduces Complications After Left Pancreatectomy
A systematic review and meta-analysis, including 15,817 patients, reveals that omitting abdominal drainage after left pancreatectomy significantly lowers major morbidity, postoperative pancreatic fistula rates, readmissions, and surgical site infections. The no-drain group demonstrated a relative risk of 0.77 for major complications and a striking 51% reduction in postoperative pancreatic fistula occurrence. Additionally, patients without drains […]
Surgery improves outcomes in metastatic neuroendocrine tumors
Evidence suggests that surgical intervention, prior to peptide receptor radionuclide therapy, significantly enhances progression-free survival for patients with metastatic gastroenteropancreatic neuroendocrine tumors. In a study of 89 well-matched patients, those who underwent surgery had a median progression-free survival of 26.1 months, compared to 15.6 months in the no-surgery group (p = .04). Furthermore, liver debulking […]
High compliance with enhanced recovery programs improves liver surgery outcomes
A study involving 706 patients highlights the significant impact of high compliance with enhanced recovery programs (ERP) on achieving textbook outcomes after elective liver surgery. Of the patients, 30.7% attained these outcomes, with 24% from the high compliance group and only 6.6% from the low compliance group. High ERP compliance notably increased the odds of […]