A new model for predicting delayed gastric emptying (DGE) in pancreatic ductal adenocarcinoma patients post-pancreatoduodenectomy has been developed and validated. Researchers identified four key predictors: days to pancreatic drain removal, pancreatic fistula presence, sepsis/septic shock, and reoperation. The model, described as a DGE risk stratification (DGERS) tool, showed strong calibration and performance during validation, with […]

A study analyzed 163 patients who underwent either robotic-assisted hemi-hepatectomy (rh) or open hemi-hepatectomy (oh). Robotic procedures demonstrated significantly less blood loss overall and achieved better postoperative outcomes, especially for left hemi-hepatectomy, which resulted in fewer complications and shorter hospital stays. In the case of right hemi-hepatectomy, rh had lower intraoperative blood transfusions but required […]

A preoperative recurrence score (PRS) model was developed to predict early recurrence in peri-hilar cholangiocarcinoma patients based on radiological features. In a study of 215 patients, significant predictors included tumor size, portal vein involvement, hepatic artery involvement, and suspicious lymph nodes. The PRS demonstrated excellent discrimination, achieving AUCs of 0.83 in internal and 0.84 in […]

A study of 471 patients undergoing pancreaticoduodenectomy and distal pancreatectomy revealed that postoperative hyperlipasemia and hyperamylasemia on the first day post-surgery are significant independent risk factors for developing postoperative pancreatic fistula. In multivariate analysis, hyperlipasemia was identified as a notable predictor of this complication, suggesting that its absence may assist in identifying low-risk patients. Integrating […]

A comprehensive meta-analysis identified several modifiable environmental factors associated with gallbladder cancer (GBC). Key risk factors included body mass index, waist circumference, and bile duct infections, all showing moderately high credibility in longitudinal studies. Interestingly, higher education levels correlated with reduced GBC risk. With 350 meta-analyses from 215 studies covering multiple exposure domains, the findings […]

A randomized controlled trial is underway to compare the safety and efficacy of a surgical stapler method versus traditional energy devices for pancreatic parenchymal transection during pancreatoduodenectomy. Initiated in September 2023, the STRAP-PD trial at Wakayama Medical University Hospital aims to evaluate its effectiveness in minimizing postoperative pancreatic fistula rates and complications among patients with […]

Surgery following neoadjuvant chemotherapy significantly improves overall survival for patients with borderline resectable and locally advanced unresectable pancreatic ductal adenocarcinoma, according to a retrospective study involving 124 patients. After applying methods to reduce selection and immortal time biases, analysis revealed marked survival advantages for those undergoing surgery compared to chemotherapy alone. This finding was supported […]

In a study involving 990 liver resection patients, persistent acute kidney injury (AKI) was linked to significantly worse postoperative outcomes, including increased morbidity, extended hospital stays, and higher 90-day mortality rates. Among 384 patients with hepatocellular carcinoma, persistent AKI correlated with poorer overall survival, identified as an independent poor prognostic factor. Key predictors of persistent […]