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A systematic review and regression analysis of 15 US-based colorectal cancer surgical trials found significant disparities in the representation and reporting of racially and ethnically diverse participants. Out of the included trials, 66.7% did not report race and 73.3% did not describe ethnicity adequately. The…
Approximately 50.2% of patients who underwent total colectomy for ulcerative colitis in the United States received ileal pouch-anal anastomosis. Younger age, lower comorbidities, elective cases, and laparoscopic approach were associated with a higher likelihood of undergoing this procedure. Socioeconomic status did not influence the decision.…
Findings from a nationwide analysis revealed that achieving a modified textbook outcome (MTO) after surgery for colorectal liver metastases (CRLM) was associated with better overall survival (OS). Out of 6,525 eligible patients, 81% achieved MTO. Between 2014 and 2018, patients achieving MTO had a 5-year…
Linked electronic health records were used to develop a risk model for 90-day mortality in patients undergoing emergency colorectal cancer (CRC) surgery. The selected model, which included additional physiological and surgical measures along with patient and tumor characteristics, showed considerably better discrimination compared to the…
Normal CEA levels (≤ 2.5 ng/ml) after neoadjuvant chemotherapy (NACT) and cytoreductive surgery with hyperthermic intraperitoneal chemoperfusion (CRS/HIPEC) are associated with better survival in patients with colorectal peritoneal metastases (CRPM). A retrospective study on 253 CRPM patients showed that those with normal CEA levels after…
Preoperative exclusive enteral nutrition (EEN) significantly decreases the risk of skin and soft tissue infections and intra-abdominal septic complications in Crohn's disease (CD) patients undergoing intestinal surgery, according to a meta-analysis of 14 nonrandomized cohort studies. The relative risk of intra-abdominal septic complications was reduced…
The study assessed the feasibility, safety, and clinical utility of a vessel-sparing approach in totally robotic sigmoidectomy for adenocarcinoma. The results showed that the completely vessel-sparing technique was feasible and safe, with a median of 21 examined lymph nodes and zero positive lymph nodes. The…
A study evaluated the safety and feasibility of a robotic true D3 lymph node dissection using a superior mesenteric vein taping technique for right colon cancer. The technique allowed for accurate exposure of the ileocolic artery and provided a good view for lymph node dissection.…
Machine learning models were developed utilizing pretreatment magnetic resonance imaging (MRI) radiomics and clinical parameters to predict neoadjuvant chemoradiotherapy response in patients with locally advanced rectal carcinoma. The impact of radiomics dimensionality on predictive performance was assessed. Two models were constructed, revealing moderately advantageous effects…
Selective lateral pelvic lymph node dissection after preoperative chemoradiotherapy has been found to decrease local recurrence in middle/low rectal cancer, providing survival benefits. The study investigated the safety, indications, and survival benefits of this procedure based on preoperative characteristics. Results showed that surgery times were…
