A quality improvement study investigated the impact of reducing postoperative laboratory testing after colorectal surgery. The intervention group showed a 33% reduction in labs per hospital stay, 26% reduction in labs per day, and a 49% increase in lab-free days. There were no differences in length of stay or readmissions between the intervention and non-intervention […]
Category: Intestine and Lower Gastrointestinal Tract
Standardized Technique and Assessment Tool for Minimally Invasive Right Hemicolectomy
Researchers achieved national consensus on the optimal and standardized technique for minimally invasive right hemicolectomy (MIrh) in colon cancer. The study involved formulating consensus statements and conducting three rounds of the Delphi technique with 76 colorectal surgeons. The development and validation of a video-based competency assessment tool (CAT) for MIrh showed high consistency among surgeons, […]
The Impact of Food Insecurity on Surgical Outcomes in Colorectal Cancer Patients
The study assessed the association between food insecurity and surgical outcomes in colorectal cancer patients. It found that high levels of food insecurity were linked to higher odds of nonelective surgery, 90-day readmission, extended length-of-stay, and complications. Patients with high food insecurity also had decreased odds of being discharged to home and achieving textbook outcomes. […]
Laparoscopic Surgery Attenuates Early Inflammatory Response in Colorectal Cancer
Researchers conducted a systematic review and meta-analysis comparing laparoscopic surgery (LS) to open surgery (OS) in patients with colorectal cancer. They found that LS resulted in milder proinflammatory reactions, as indicated by lower concentrations of inflammatory markers such as interleukins and C-reactive protein. The difference was particularly notable within the first 9 hours after surgery. […]
Ex Vivo Expanded Allogeneic Mesenchymal Stem Cells Provide Durable Treatment for Fistulizing Crohn’s Disease
The results of three phase Ib/IIa clinical trials show that treatment with ex vivo expanded allogeneic bone marrow-derived mesenchymal stem cells is safe and effective for severe perianal, rectovaginal, and peripouch fistulizing Crohn’s disease. At 6 months, 83.3% of perianal, 33.3% of rectovaginal, and 30.8% of pouch fistula treatment cohorts achieved combined clinical and radiographic […]
Complete mesocolic excision in right colon cancer: Higher lymph node yield and improved surgical quality
Interim analysis of a randomized Phase III trial comparing complete mesocolic excision (CME) with conventional surgery for right colon cancer showed that CME was associated with a significantly higher lymph node yield (25 vs. 20) and improved surgical quality indicators. No differences were observed in complications, mortality, or surgery duration. Hospital stay was even shorter […]
Intestinal Autotransplantation Results in Prolonged Survival for Locally Advanced or Recurrent Colon Cancer Involving SMA
Intestinal autotransplantation (iatx) combined with extended resections of multiple organs, including the superior mesenteric artery (SMA), was performed on 10 patients with locally advanced or recurrent colon cancer invading the SMA. The study found that iatx, either alone or in combination with pancreaticoduodenectomy, is a safe procedure and is associated with a 68% recurrence-free survival […]
Percutaneous Creation of Gastrointestinal Anastomosis via Lumen-Apposing Metallic Stents for Gallbladder Drainage
Researchers discuss the emerging frontier of percutaneous cholecysto-enteric anastomoses for internal drainage of the gallbladder, focusing on the percutaneous delivery and deployment of lumen-apposing metallic stents. The study highlights the efficacy and safety of using these stents for creating gastrointestinal anastomosis, providing a less invasive option for gallbladder drainage compared to traditional surgical procedures. Journal […]
Enhancing R0 Resection in Anorectal Cancers: A Posterior-First, 2-Stage Approach
Using a posterior-first, 2-stage approach, researchers achieved consistent R0 resection of locally advanced primary and recurrent anorectal cancers involving the deep pelvic sidewall. All 10 patients in the study achieved R0 resection, although nine experienced complications, including gluteal wound issues. Four patients developed metastatic disease during follow-up, highlighting the importance of close monitoring. Overall, the […]
Enhanced Recovery Programs and Colorectal Surgery Outcomes: reduces Racial Disparities in Complications, but not in Length of Stay
The study aimed to determine the impact of enhanced recovery programs on social vulnerability and race-related disparities in colorectal surgery outcomes. The researchers found no significant association between social vulnerability and length of stay, complications, or readmissions in either the enhanced recovery or non-enhanced recovery groups. Black race was associated with increased length of stay […]