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Rectal cancer patients with a positive circumferential resection margin (CRM) due to direct tumor involvement face a worse prognosis than those with indirect causes. Analyzing 1460 cases, 85 had positive CRMs, with direct involvement linked to increased local recurrence. Kaplan-Meier analysis showed better overall and…
Colorectal carcinoma with sarcomatoid components is a rare and aggressive subtype of colorectal cancer. In this study, researchers reported 15 cases of this subtype and reviewed the existing literature. The tumors were predominantly found in the rectosigmoid region and presented with symptoms such as abdominal…
The systematic review and meta-analysis of studies investigating the association of surgical technique with outcomes for colorectal liver metastases (crlm) found that anatomic resection (AR) was associated with improved liver-specific disease-free survival (DFS) and overall DFS in patients with mutras tumors. Specifically, AR resulted in…
Preliminary evidence from a retrospective study using the New York State SPARCS database suggests that female surgeons have better post-operative outcomes than their male colleagues in predominantly female patient surgeries. The study examined the impact of patient-surgeon gender discordance on outcomes in bariatric, foregut, and…
The AGA Clinical Practice Guideline on the Management of Pouchitis and Inflammatory Pouch Disorders provides practitioners with recommendations for the prevention and treatment of pouchitis, Crohn's-like disease of the pouch, and cuffitis. The guideline panel made 9 conditional recommendations, including the use of antibiotics for…
Researchers analyzed retrospective data from high-resolution anorectal manometry and patient-completed bowel habit and symptom diaries to evaluate the usefulness of the diary as a screening tool for disordered rectoanal coordination (DRC). They found that patients with a dyssynergic pattern (DP) during manometry had a higher…
A retrospective cohort study analyzed molecular profiling and mutation rates in stage IV colorectal cancer (CRC) patients. The study found significant increases in molecular testing rates for microsatellite instability (MSI), KRAS, and BRAF mutations over time. Black patients had higher odds of testing for MSI…
Expert consensus was achieved on the definition of textbook oncologic outcomes (TOO) in cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) for colorectal peritoneal metastasis. The consensus criteria included the absence of unplanned re-operations, severe postoperative complications, unplanned readmissions, 90-day postoperative mortality, and contraindications for…
Patients with mutras colorectal liver metastases (crlm) may benefit from anatomic resection (AR) compared to nonanatomic resection (NAR), according to a systematic review and meta-analysis. The study found that AR was associated with a significant improvement in liver-specific disease-free survival and overall disease-free survival among…
Researchers aimed to determine the minimum number of lymph nodes (lns) needed to accurately stage adenocarcinoma of the appendix. They analyzed data from 3,602 patients and found that harvesting at least ten lns was necessary to minimize the risk of missing lymph node positive (lnp)…
