Neoadjuvant calcium electroporation was found to be a safe and feasible treatment modality for potentially curable colorectal cancer. In a study of 21 patients, no procedure-related complications were reported, and surgery was able to be performed as planned in 19 patients. Limited side effects and no significant impact on quality of recovery or inflammatory markers […]
Category: Intestine and Lower Gastrointestinal Tract
Effect of Online Educational Modules on Anastomotic Leak Rates Following Right Colectomy
The EAGLE study aimed to reduce anastomotic leak rates following right colectomy through a standardized quality improvement intervention. The study included 332 hospital teams from 64 countries, with completion of online educational modules by half of the surgeons. The primary analysis showed that completion of the educational modules significantly decreased leak rates in high-engagement centers […]
Increased Incidence of Gastrostomy Tube Placement in Surgical Necrotizing Enterocolitis
Approximately 56.3% of infants with surgical necrotizing enterocolitis (NEC) required gastrostomy tube (GT) placement after ostomy reversal. GT placement may be safely performed concurrently with ostomy reversal, reducing the need for an additional procedure. Gestational age and birth weight did not significantly differ between patients who did and did not require GT placement. The hospital […]
Comparison of Laparoscopic Parastomal Hernia Repair Techniques: Keyhole, Sugarbaker, Sandwich, and Hybrid
Parastomal hernia, a common complication after stoma formation, has been treated using various minimally invasive techniques. However, the optimal technique remains unclear. In this updated systematic review and meta-analysis, researchers analyzed 33 studies involving 1289 patients to compare the outcomes of four commonly used techniques. The keyhole technique showed the highest incidence of complications and […]
Surgical Principles for Small Bowel Neuroendocrine Tumor Resection
Small bowel neuroendocrine tumors (SB-NETs) are increasingly identified and have become the most frequent entity among small bowel tumors. Surgical treatment goals include control of tumor volume, endocrine secretion, and prevention of locoregional complications. The study presents eight steps for systematic surgical planning and execution of resection. The role of primary tumor resection in the […]
Long-term Survival in Patients with Colorectal Peritoneal Carcinomatosis Treated with CRS/HIPEC
Actual 5-year survival rates after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS/HIPEC) for patients with peritoneal carcinomatosis (PC) of colorectal origin were reported in this study. A total of 103 patients were analyzed, with a median follow-up of survivors at 88 months. The 5-year overall survival (OS) was 36%, and the median OS was 42.5 […]
Colorectal Surgery Postdischarge App: Enhancing Satisfaction, Impact on 30-Day Readmission Limited
A randomized controlled trial evaluated the effectiveness of a postdischarge mobile app in reducing 30-day readmissions and improving patient-reported outcomes after elective colorectal surgery. The app did not significantly reduce readmissions or emergency room visits, but it led to significant improvements in patient satisfaction, well-being, and reduced anxiety levels. While the app may not reduce […]
Total Neoadjuvant Therapy for Rectal Cancer: Impact on Surgical Outcomes and Pathology
In a meta-analysis of 11 randomized controlled trials involving 3,185 rectal cancer patients, researchers compared total neoadjuvant therapy (TNT) to standard long course chemoradiotherapy (LCRT). TNT did not significantly differ in mortality or major complications but increased the risk of breached total mesorectal excision (TME). However, TNT showed a lower risk of disease progression during […]
Perioperative Chemotherapy Improves Overall Survival in Synchronous Colorectal Liver Metastases
Analyzing 72,376 patients with colorectal liver metastases (CRLM) from the National Cancer Database, researchers found that liver-only CRLM patients undergoing perioperative chemotherapy had a superior median overall survival (OS) of 44.7 months. Resection of both primary and metastatic sites also correlated with better OS (38.9 months) compared to metastatic site alone (30.2 months) or primary […]
Pelvic Exenterations and Cytoreductions Safely Combined for T4 Rectal Cancers with Peritoneal Metastasis
Investigating the combination of pelvic exenterations and cytoreductions in T4 rectal cancers with peritoneal metastasis, a study on 39 patients (median age 35) revealed safety in terms of morbidity (18% major complications). Although achieving CC-0 in 97.4%, hyperthermic intraperitoneal chemotherapy was administered to 15 patients. Despite safety, overall and recurrence-free survival remained modest at 17 […]