A bibliometric study of 1,608 articles from 1994 to 2024 highlights the evolving landscape of anal fistula treatment in Crohn’s disease. Researchers identified significant contributions from 325 countries, with the US and UK leading in publication volume. The Cleveland Clinic and Imperial College London emerged as influential institutions. Trends show a focus on surgical interventions, […]
Category: Intestine and Lower Gastrointestinal Tract
Bismuth subgallate-borneol ointment enhances healing in surgical wounds
A novel bismuth subgallate-borneol compound ointment significantly improved wound healing in infectious postoperative wounds after anorectal surgery. In a randomized controlled trial involving 46 patients, the experimental group showed a higher granulation growth rate at all observation points and a notable increase in wound healing rate by day 14 compared to the control group. These […]
Methylated ctDNA predicts outcomes in liver metastases treatment
A prospective study of 56 colorectal cancer patients reveals that preoperative circulating tumor DNA (meth-ctDNA) serves as a significant biomarker for assessing treatment plans. Negative preoperative meth-ctDNA correlates with longer median progression-free survival (PFS), identified as a strong independent predictor (HR=3.3). Similarly, negative postoperative meth-ctDNA also indicates improved survival outcomes. This study suggests that assessing […]
Laparoscopic surgery shows benefits for metachronous colorectal cancer patients
In a comparative study of 59 patients with metachronous colorectal cancer, laparoscopic surgery demonstrated significant advantages over open surgery. Patients who underwent laparoscopic procedures experienced less blood loss (56.80 ml vs. 136.47 ml), faster recovery of bowel function, and shorter hospital stays (7.24 days vs. 10.79 days). Additionally, those in the laparoscopic group returned to […]
Transanal TME shows equivalent disease-free survival compared to laparoscopic TME.
In a study involving 1,115 patients with mid-low rectal cancer, transanal total mesorectal excision (TME) demonstrated a 3-year disease-free survival rate of 82.1%, while laparoscopic TME showed 79.4%, indicating noninferiority. The local recurrence rates were 3.6% and 4.4%, respectively. Additionally, overall survival rates were 92.6% for transanal TME and 90.7% for laparoscopic TME. These findings […]
Outcomes of Pelvic Pouch Procedure Highlight Risks and Survival Rates
Over a 40-year analysis involving 5,070 patients, significant differences in pouch survival rates were observed among various diagnoses. Ulcerative colitis (UC) had a 20-year survival rate of 92%, while Crohn’s disease (CD) was lower at 87%. Patients with familial adenomatous polyposis (FAP) exhibited the best outcomes, with a 95% survival rate and fewer complications. However, […]
Preoperative tumor markers predict surgical outcomes in peritoneal metastases
Clustering preoperative tumor marker patterns aids in predicting surgical outcomes for patients with peritoneal metastases. Among 138 with pseudomyxoma peritonei (pMP), two distinct clusters emerged—pMP cluster-1 had a 5-year overall survival rate of 77%, while pMP cluster-2 faced a significantly poorer prognosis of 36%. A similar pattern was observed in 213 colorectal peritoneal metastases patients, […]
Early refeeding reduces complications after colorectal cancer surgery.
A study involving 275 colorectal cancer patients revealed that early postoperative refeeding significantly reduces the risk of infectious complications and hospital stays exceeding five days. Specifically, late refeeding, use of nasogastric tubes, and intra-abdominal drains were identified as factors that increase complications. The findings indicate that early refeeding should be prioritized to enhance recovery and […]
Rising colon and rectum cancer rates projected through 2030
Colon and rectum cancer (CRC) continues to rise in China, with 658,321 cases reported in 2021, predominantly in males. The incidence rate for males was 42.24 per 100,000, compared to 21.87 for females, with male mortality rates significantly higher. Projections indicate further increases, particularly among younger males influenced by lifestyle factors such as smoking and […]
Preoperative blood count factors predict early colorectal cancer metastasis
In a study of 268 resected colorectal cancer cases, researchers found that preoperative complete blood count parameters can significantly predict early liver and lung metastases. Decreased red blood cells, lymphocytes, and an elevated monocyte-to-lymphocyte ratio correlated with liver metastases, while lower eosinophil counts were linked to lung metastases. Composite scores highlighting these factors revealed a […]