Neutrophil to lymphocyte ratio (NLR) > 6.8 was identified as the sole independent predictive factor for bowel ischemia in non-strangulated adhesive small bowel obstruction, with 78% sensitivity and 65% specificity. This study highlights the importance of NLR as a straightforward and reproducible parameter in predicting bowel ischemia onset, aiding acute care surgeons in early detection […]
Category: Intestine and Lower Gastrointestinal Tract
Long-Term Outcomes of Additional Surgery for T1 Colorectal Cancer
Study comparing long-term outcomes of patients treated with additional surgery after endoscopic resection versus primary surgery for T1 colorectal cancer found no adverse effects on overall survival rates. The 5-year survival rates were 97.1% in the additional surgery group and 96.0% in the primary surgery group, indicating non-inferiority. Additionally, recurrence rates showed no significant difference […]
Delayed Adjuvant Chemotherapy Linked to Poorer Colorectal Cancer Survival
Delaying adjuvant chemotherapy for more than 6 weeks post colorectal cancer surgery is associated with worse disease-free survival in high-risk stage II and III patients. A study of 5719 individuals revealed a 5-year disease-free survival of 78.0% vs. 73.2% in early vs. late-start groups, respectively. Those initiating chemotherapy later had a hazard ratio of 1.24 […]
Similar Parastomal Hernia Recurrence Rates in Open Sugarbaker vs Keyhole Mesh Repair
A randomized clinical trial compared open retromuscular Sugarbaker and keyhole mesh placements for parastomal hernia repair over 2 years in 150 patients. At the 2-year mark, parastomal hernia recurrence rates were similar between the two groups. There were no significant differences in reoperations, complications, or patient-reported outcomes between the techniques. Further advancements are needed to […]
Endoscopic Ultrasonography for Residual Rectal Neuroendocrine Tumor Diagnosis
Endoscopic ultrasonography (EUS) is a sensitive method for identifying residual rectal neuroendocrine tumors (NETs) post-resection. EUS detection, with a high sensitivity of 94%, is superior to visual detection. Salvage endoscopic treatment, incorporating EUS, is safe and effective in managing incompletely resected NETs, with no recurrence observed in patients during follow-up. EUS shows promise in accurately […]
Overlap Anastomosis Outperforms End-to-End in Laparoscopic Colorectal Cancer Surgery
Overlap anastomosis showed superior outcomes compared to functional end-to-end anastomosis in laparoscopic colorectal cancer surgery, with shorter operation and recovery times and lower post-operative complication rates. These findings suggest that overlapping anastomosis can expedite intestinal function recovery without compromising patient quality of life or survival in the short term post-surgery. Comparative Study by Sun W […]
Extended Pharmacologic Prophylaxis Improves Survival in Colon Cancer Patients
Extended pharmacologic prophylaxis after colon cancer surgery is associated with improved overall and cancer-specific survival. Results suggest a potential anti-neoplastic effect from heparin derivatives in preventing post-surgical venous thromboembolism. A large database study of 20,102 patients showed significantly higher survival rates in patients who received extended prophylaxis. Multivariable analysis demonstrated a reduced risk of death […]
CRP-to-Albumin Ratio Predicts Anastomotic Leakage in Rectal Cancer Patients Using ICG-FI
Preoperative C-reactive protein-to-albumin ratio (CAR) ≥ 0.049 was identified as an independent risk factor for anastomotic leakage (AL) in rectal cancer patients undergoing surgery with intraoperative indocyanine green fluorescence imaging (ICG-FI). CAR could serve as a criterion for early surgical intervention or consideration of interventions like diverting stoma creation, potentially lowering the incidence of AL […]
Key Risk Factors for Rectal Cancer Recurrence
Success in rectal cancer treatment depends on predicting recurrence risks. Swedish registry data on 9428 patients revealed major impacts on distant recurrence from factors like pt4a, pn2b, tumor deposit, lymph node yield, and tumor level. Pathologic stage and identified risk factors guided different recurrence risks across treatment groups. Recognizing key risk factors alongside stage allows […]
Multidisciplinary conferences enhance survival in colorectal liver metastases
Assessment by a multidisciplinary team conference, particularly with a liver surgeon present, was linked to better overall survival in patients with synchronous colorectal liver metastases. Patients residing near a hospital with a hepatobiliary unit were more likely to receive liver surgery and had improved median survival. Geographical location influenced access to treatment, with no observed […]