Colorectal signet-ring cell carcinoma (CSRCC) is a rare entity with poor prognosis, often diagnosed at advanced stages. Studies show an incidence of 0.1%-2.4%, associated with lower survival rates than other adenocarcinomas. Surgical intervention is challenging, and exploratory laparoscopy is advised to assess peritoneal metastases. Tailored treatment approaches are necessary due to the unique characteristics of […]
Category: Intestine and Lower Gastrointestinal Tract
Lymph Node Staging Systems and Prognosis of Colorectal Neuroendocrine Neoplasms
Colorectal neuroendocrine neoplasms prognosis in surgical treatment can be predicted by lymph node staging systems like LNR, PLN, and LODDS. A cohort study of 895 patients showed significant predictive values for mortality. After adjusting confounders, these systems were linked with patient outcomes, proving their effectiveness in assessing prognosis. This study highlights the importance of lymph […]
Long-term Risk Reduction After Colonoscopy for Colorectal Cancer
Colorectal cancer risk remains lower more than 15 years post-colonoscopy, challenging current screening guidelines. A population-based study in Ontario, Canada, with over 5 million participants showed reduced cancer incidence and mortality at all timepoints up to 15 years, even after the procedure. Individuals with negative colonoscopy results had significantly lower risk. The study suggests a […]
Laser Hemorrhoidoplasty Reduces Pain and Bleeding Over Conventional Hemorrhoidectomy
Diode laser hemorrhoidoplasty demonstrates superiority over conventional hemorrhoidectomy in reducing operative blood loss, postoperative hemorrhage, operative time, and postoperative pain score. However, there is no significant difference in complications such as fecal/flatus incontinence, urinary retention, and hemorrhoid recurrence. Subgroup analyses support these findings, highlighting the benefits of laser hemorrhoidoplasty in terms of minimizing postoperative complications […]
Endoscopic Therapy is Safe and Effective for Stoma Closure Site Strictures in Ileal Pouches
Endoscopic therapy is safe and effective for stoma closure site strictures in patients with ileal pouches, providing symptomatic relief and avoiding surgery. Immediate technical success was achieved in 90.4% of interventions, with no need for surgical intervention during follow-up. Post-procedural complications were minimal, with 66.7% of patients reporting symptom improvement. Both endoscopic balloon dilation and […]
Real-time Detection of Active Bleeding in Laparoscopic Colectomy using AI
Developing a real-time AI model to detect active intraoperative bleeding, this study achieved an average precision of 0.574 for active bleeding and 48.5 frames per second. Surgeons rated the sensitivity and overdetection areas of the model highly, indicating its potential to improve surgical outcomes by providing real-time support in laparoscopic colectomy. The AI model can […]
Perioperative Inflammatory Indicators Predict Disease-Free Survival in Rectal Cancer
Perioperative inflammatory indicators, including preoperative neutrophil-to-lymphocyte ratio (NLR) and postoperative systemic immune-inflammation index (SII), are crucial for predicting 3-year disease-free survival (DFS) in rectal cancer patients. A nomogram based on TNM stage III and neural invasion effectively stratifies high-risk patients, enabling timely postoperative follow-up and adjuvant treatment. The model demonstrates good discrimination and calibration, highlighting […]
EndoRobotic Submucosal Dissection for Colorectal Neoplasia
EndoRobotic Submucosal Dissection using the da Vinci SP platform showed a 100% en-bloc resection rate in 28 patients with colorectal neoplasms. There were no intraoperative complications or mortality, with only two minor postoperative complications. Pathology outcomes revealed a mix of benign and malignant lesions, indicating the procedure’s safety and feasibility. Further studies are needed to […]
Collagen Changes in Distal Anastomotic Margin and Anastomotic Stenosis
Neoadjuvant chemoradiotherapy for rectal cancer can alter collagen structure, increasing the risk of postoperative anastomotic stenosis. A retrospective study with 371 patients revealed that collagen score (CS) is an independent risk factor for anastomotic stenosis. A predictive nomogram based on CS accurately identified individuals at risk for postoperative anastomotic stenosis, with good discrimination and validation […]
Prognostic Indicators for Mucinous Appendiceal Neoplasm Patients
Identification of reliable prognostic indicators for different groups of appendiceal mucinous neoplasm patients revealed the Completeness of Cytoreduction (CC) score as a consistent predictor of survival. The Peritoneal Cancer Index (PCI) showed significance in specific subtypes, while the Prior Surgical Score (PSS) predicted outcomes in certain patient groups. Symptomatic patients or those with extensive systemic […]