The study showed that simultaneous resection of liver metastases combined with HIPEC resulted in a significantly higher complete resection rate, total effective rate, and negative change of CEA compared to resection alone. This approach demonstrated superior efficacy in treating synchronous colorectal cancer liver metastases, potentially extending patient survival and improving quality of life. Journal Article […]
Category: Intestine and Lower Gastrointestinal Tract
Post-Discharge Outcomes for Acute Diverticulitis: Primary Anastomosis vs. Hartmann’s Procedure
Primary anastomosis with diverting loop ileostomy showed higher 1-year ostomy closure rates and less complications upon stoma closure compared to Hartmann’s procedure for acute diverticulitis. Despite increased unplanned readmissions, primary anastomosis patients had favorable outcomes, supporting guidelines favoring this approach. Journal Article by Rios Diaz AJ, Bevilacqua LA (…) Palazzo F et 5 al. in […]
Survival Discrepancies in Colon Cancer Staging
Survival paradox persists between stage IIB/C and IIIA colon cancer, even after adjusting for chemotherapy and lymph node retrieval. Optimal treatment for IIIA yields significantly better 5-year survival rates compared to IIB/C. Stage remains an independent predictor of overall survival, with significant differences in survival outcomes between different sub-stages. The TNM system should consider revising […]
Outpatient Management and Antibiotic Use in Acute Diverticulitis
Outpatient observation for acute diverticulitis (Hinchey 1a) and no antibiotics resulted in lower recurrence rates and shorter hospital stays compared to inpatient treatment and antibiotics. Recurrence, hospital admissions, and mortality rates were similar between outpatient and inpatient management. Future studies are needed to confirm the effectiveness of observation-only and antibiotics-free approaches in managing uncomplicated acute […]
Multiple Disease-Modifying Drugs Increase Surgical Risk in Ulcerative Colitis
Study finds using multiple disease-modifying drugs in ulcerative colitis increases risk of surgical resection. Each additional drug significantly raises likelihood of surgery, highlighting importance of patient counseling. However, postoperative risk of complications, ER visits, and readmissions remain unaffected by number of drugs used. Findings offer crucial prognostic insights for clinicians managing UC patients. Journal Article […]
Long-term outcomes of laparoscopic surgery for very low rectal cancers: high anus preservation and moderate functional outcomes
Patients undergoing laparoscopic surgery for stage I ultra-low rectal cancers near the anal verge showed a 3-year local recurrence rate of 6.3%. Anus-preserving surgery was successful in 93% of cases, leading to high rates of functional preservation, with moderate improvements in anal function and acceptable incontinence scores. Urinary function recovered rapidly post-surgery, but sexual function […]
Antibiotic Use Prior to Ileal Pouch-Anal Anastomosis Increases Pouchitis Risk
Researchers found that antibiotic exposure in the 12 months before Ileal Pouch-Anal Anastomosis (IPAA) surgery for ulcerative colitis increased the risk of developing pouchitis in the first 2 years post-surgery. Compared to those without antibiotic prescriptions, patients with 1-2 courses had a 30% increased risk, while those with 3 or more courses had a 77% […]
Management of Right-Sided Diverticulitis: North African Experience
Researchers conducted a retrospective study on 40 patients with right-sided diverticulitis in a North African surgical center. They found that conservative management was successful in 14 cases, while 26 patients underwent operative procedures with no postoperative events and a short hospital stay. Follow-up showed no recurrences, indicating that right-sided diverticulitis has a lower complication rate […]
Appendectomy is associated with a milder clinical course in Crohn’s disease
In a nationwide cohort study, Crohn’s disease patients who had previously undergone appendectomy had a lower rate of CD-related hospital admissions and were less likely to initiate treatment with biologics or undergo colorectal resections compared to those without appendectomy. Rates of small bowel resections were comparable between the two groups. Appendectomy performed after CD diagnosis […]
Preoperative Ureteral Stent Placement and Intraoperative Ureteral Injury
Preoperative ureteral stent placement during colorectal surgery did not lead to earlier detection of ureteral injury. Of 6481 patients, 15% had stents placed, with 0.4% experiencing a ureteral injury. Hematuria and UTI risk increased with stent use, but intraoperative identification of injury was not associated with stent placement. Iatrogenic ureteral injury was rare, contrasting with […]