Category: Intestine and Lower Gastrointestinal Tract

Higher cardiovascular health scores linked to lower colorectal cancer risk

A recent population-based study found that higher scores on life’s essential 8 (LE8), a cardiovascular health metric, significantly correlate with a reduced prevalence of colorectal cancer (CRC) among U.S. adults. Those with the highest LE8 scores experienced an 81% lower risk of CRC compared to individuals with the lowest scores. The inverse relationship appears linear, […]

NIRF and SCEUS enhance detection of colorectal liver metastases

A dual-center study involving 69 patients demonstrated that near-infrared fluorescence imaging (NIRF) combined with Sonazoid contrast-enhanced ultrasound (SCEUS) significantly improves the detection of colorectal liver metastases (CRLMs) during laparoscopic surgery. NIRF+SCEUS identified 285 lesions, outpacing the 234 detected by white light and intraoperative ultrasound. Notably, this approach changed the surgical strategy for 40.6% of patients […]

Chyme reinfusion reduces complications after surgical reconstruction

A meta-analysis of five studies with 460 patients revealed that chyme reinfusion (CR) significantly lowers overall complications (odds ratio 0.25) and specifically ileus (odds ratio 0.35) and diarrhea (odds ratio 0.29) in patients undergoing reconstruction for high-output ostomies and enterocutaneous fistulas. Additionally, CR notably shortens hospital stays and reduces inflammatory markers like C-reactive protein and […]

Gum chewing outperforms coffee for bowel recovery post-cesarean

A systematic review included 20 studies with 2,876 patients, comparing coffee and gum chewing effects on bowel recovery after cesarean sections. Both interventions significantly reduced the time to first defecation and flatus versus control. Although gum chewing proved superior for overall recovery, reducing complications, improving patient satisfaction, and shortening hospital stays, coffee enhanced food tolerance […]

Surgical treatment for hemorrhoids offers better outcomes

A meta-analysis of seven studies involving 760 patients demonstrates that surgical intervention for hemorrhoids significantly surpasses conservative methods in achieving complete symptom resolution (odds ratio = 2.96, p < 0.001) and reducing pain scores (standard mean difference = -0.93, p = 0.02). Though both treatment options showed similar postoperative complications, surgery provided faster recovery, particularly […]

Mosapride accelerates recovery of gastrointestinal motility post-surgery

Mosapride significantly enhances gastrointestinal recovery following elective colorectal cancer surgery. In a randomized controlled trial involving 44 patients, those receiving mosapride experienced their first bowel movement in an average of 26 hours compared to 50 hours for the control group (p=0.004). Similarly, the time to passage of flatus was reduced from 70 hours to 40 […]

New guidelines prioritize systemic therapy for colorectal cancer with peritoneal metastases

Consensus guidelines for managing colorectal cancer with peritoneal metastases emphasize early referral to specialized centers. A national panel achieved over 90% consensus on clinical pathways, favoring systemic therapy over upfront surgery in synchronous cases. In metachronous cases, risk stratification was updated. Although the overall evidence remains low, the guidelines represent significant progress in addressing optimal […]

Perioperative probiotics may significantly lower infection rates after surgery

A meta-analysis of 28 randomized controlled trials with 2,686 participants revealed that perioperative probiotics and synbiotics are linked to a significant reduction in total postoperative infection rates after elective colorectal surgery. Specifically, the use of these interventions correlated with nearly a 50% decrease in infections within 30 days post-surgery (relative risk 0.55, p < 0.001). […]

Robotic surgery shows advantages in mid-low rectal cancer treatment

A predictive model developed for anastomotic complications in mid-low rectal cancer highlights robotic surgery’s advantages over laparoscopic methods. Although robotic surgery entails longer operative times, patients experience earlier recovery milestones such as first flatus and liquid diets without ileostomy. Oncological outcomes and overall complication rates remain comparable between both techniques. The model, incorporating seven clinical […]

Lidocaine outperforming nifedipine in hemorrhoid pain relief

A retrospective cohort study of 123 acute hemorrhoidal disease patients revealed that a treatment regimen including oral diosmin/hesperidin, bromelain, and topical lidocaine resulted in faster pain relief and improved symptom scores compared to a nifedipine-based regimen. Significant differences were noted by day 7 in pain scores (0.17 vs. 2.20, p < 0.001) and the hemorrhoidal […]