The study aimed to evaluate the role of immunocyte-derived ratios (IDRs) as potential markers for postoperative recovery of gastrointestinal function after colorectal cancer surgery. The retrospective analysis of 260 patients revealed a positive correlation between IDRs (systemic immune-inflammation index, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio) and the i-feed score, indicating improved gastrointestinal motility. IDRs, along with other […]
Category: Intestine and Lower Gastrointestinal Tract
Fredet’s Fascia: Implications for Safer Right Hemicolectomies in the CME Era
The study reviewed medical literature to assess the use and clinical significance of Fredet’s fascia in complete mesocolic excision (CME) for right-sided colon adenocarcinoma. The results showed limited utilization of the term “Fredet’s fascia” in English medical literature and conflicting definitions and boundaries. The researchers emphasized the importance of understanding Fredet’s fascia in surgical procedures […]
The Role of Adipose Tissue Mesenchymal Stem Cells in Preventing Anastomotic Leak in Colonic Surgery
Adipose tissue-derived mesenchymal stem cells (ADMSCs) were investigated for their potential in reducing inflammation and preventing anastomotic leak in rats with inflammatory bowel disease. Rats were divided into four groups, and those with induced intestinal inflammation were treated with ADMSCs prior to surgery. The study found that ADMSCs effectively attenuated inflammation and significantly reduced the […]
Defining Success in Colorectal Peritoneal Metastasis Surgery: International Consensus and Improved Survival
An international consensus has been reached on the definition of textbook oncologic outcomes (TOO) in cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) for colorectal peritoneal metastasis. The TOO parameters for CRS/HIPEC in this context include absence of certain complications, achievement of complete cytoreduction, and no contraindications for chemotherapy. A study cohort of 251 patients […]
Perioperative Chemotherapy Linked to Superior Overall Survival in Patients with Colorectal Liver Metastases
Perioperative chemotherapy is associated with superior overall survival in patients with synchronous colorectal liver metastases. Resection of both the primary and metastatic sites is linked to better overall survival. The study also found that patients who received perioperative chemotherapy had significantly longer overall survival compared to those who had preoperative or postoperative chemotherapy alone. Additionally, […]
No Significant Benefit of Omental Pedicled Flap in Preventing Anastomotic Leak After Rectal Cancer Surgery
Researchers assessed the impact of omental pedicled flap (OPF) on anastomotic leak in patients undergoing low anterior resection for rectal cancer. Out of the 853 patients included in the study, OPF was utilized in 12.4% of cases. The analysis revealed that OPF use did not affect the occurrence of anastomotic leaks or operative blood loss. […]
Predictive Factors for Early Recurrence in Metastatic Colorectal Cancer Treated with Combined Liver Resection and HIPEC
The study aimed to identify predictive factors for early recurrence and survival outcomes in colorectal cancer patients with liver and peritoneal metastases who underwent combined liver resection, cytoreductive surgery, and hyperthermic intraperitoneal chemotherapy. The results showed that patients with advanced primary tumors (PT4 and/or PN2 status) had a higher risk of early recurrence, while retroperitoneal […]
Surgical Management Guidelines for Gastrointestinal Neuroendocrine Neoplasms Provide Individualized Approach
Surgical oncologists face the challenge of managing gastrointestinal midgut neuroendocrine neoplasms (NENs), particularly neuroendocrine tumors (NETs). While guidelines offer valuable insights, they rely on expert opinions and retrospective evidence. This review outlines recent recommendations for managing midgut NETs, emphasizing the need for individualized approaches based on tumor behavior, endocrine syndrome association, and prognosis. Staying updated […]
A Proposed Clinical Synoptic Operative Report Improves Documentation of Ileocolic Resection for Crohn’s Disease
Researchers conducted a retrospective analysis of 66 ileocolic resections (ICR) in 63 Crohn’s disease patients to evaluate the completeness of operative reports. They found that crucial information, such as the examination of bowel for macroscopic disease and the extent of mesenteric resection, was often poorly documented in standard operative reports. However, the proposed clinical synoptic […]
Minimum of Ten Regional Lymph Nodes Needed to Adequately Stage Adenocarcinoma of the Appendix
The study aimed to determine the minimum number of regional lymph nodes (LNs) required to accurately stage adenocarcinoma of the appendix (AC). The researchers analyzed data from 3,602 AC patients and found that harvesting at least ten LNs was necessary to minimize the risk of missing LN-positive disease. Examining fewer than ten LNs was an […]