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Intestine and Lower Gastrointestinal Tract

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Am J Gastroenterol22 Jun 2024

Long-Term Outcomes of Additional Surgery for T1 Colorectal Cancer

Study comparing long-term outcomes of patients treated with additional surgery after endoscopic resection versus primary surgery for T1 colorectal cancer found no adverse effects on overall survival rates. The 5-year survival rates were 97.1% in the additional surgery group and 96.0% in the primary surgery…

JAMA Surg22 Jun 2024

Delayed Adjuvant Chemotherapy Linked to Poorer Colorectal Cancer Survival

Delaying adjuvant chemotherapy for more than 6 weeks post colorectal cancer surgery is associated with worse disease-free survival in high-risk stage II and III patients. A study of 5719 individuals revealed a 5-year disease-free survival of 78.0% vs. 73.2% in early vs. late-start groups, respectively.…

JAMA Surg22 Jun 2024

Similar Parastomal Hernia Recurrence Rates in Open Sugarbaker vs Keyhole Mesh Repair

A randomized clinical trial compared open retromuscular Sugarbaker and keyhole mesh placements for parastomal hernia repair over 2 years in 150 patients. At the 2-year mark, parastomal hernia recurrence rates were similar between the two groups. There were no significant differences in reoperations, complications, or…

Intestine and Lower Gastrointestinal Tract22 Jun 2024

Endoscopic Ultrasonography for Residual Rectal Neuroendocrine Tumor Diagnosis

Endoscopic ultrasonography (EUS) is a sensitive method for identifying residual rectal neuroendocrine tumors (NETs) post-resection. EUS detection, with a high sensitivity of 94%, is superior to visual detection. Salvage endoscopic treatment, incorporating EUS, is safe and effective in managing incompletely resected NETs, with no recurrence…

Intestine and Lower Gastrointestinal Tract22 Jun 2024

Overlap Anastomosis Outperforms End-to-End in Laparoscopic Colorectal Cancer Surgery

Overlap anastomosis showed superior outcomes compared to functional end-to-end anastomosis in laparoscopic colorectal cancer surgery, with shorter operation and recovery times and lower post-operative complication rates. These findings suggest that overlapping anastomosis can expedite intestinal function recovery without compromising patient quality of life or survival…

Ann Surg20 Jun 2024

Extended Pharmacologic Prophylaxis Improves Survival in Colon Cancer Patients

Extended pharmacologic prophylaxis after colon cancer surgery is associated with improved overall and cancer-specific survival. Results suggest a potential anti-neoplastic effect from heparin derivatives in preventing post-surgical venous thromboembolism. A large database study of 20,102 patients showed significantly higher survival rates in patients who received…

Surg Endosc20 Jun 2024

CRP-to-Albumin Ratio Predicts Anastomotic Leakage in Rectal Cancer Patients Using ICG-FI

Preoperative C-reactive protein-to-albumin ratio (CAR) ≥ 0.049 was identified as an independent risk factor for anastomotic leakage (AL) in rectal cancer patients undergoing surgery with intraoperative indocyanine green fluorescence imaging (ICG-FI). CAR could serve as a criterion for early surgical intervention or consideration of interventions…

Intestine and Lower Gastrointestinal Tract19 Jun 2024

Key Risk Factors for Rectal Cancer Recurrence

Success in rectal cancer treatment depends on predicting recurrence risks. Swedish registry data on 9428 patients revealed major impacts on distant recurrence from factors like pt4a, pn2b, tumor deposit, lymph node yield, and tumor level. Pathologic stage and identified risk factors guided different recurrence risks…

HPB (Oxford)18 Jun 2024

Multidisciplinary conferences enhance survival in colorectal liver metastases

Assessment by a multidisciplinary team conference, particularly with a liver surgeon present, was linked to better overall survival in patients with synchronous colorectal liver metastases. Patients residing near a hospital with a hepatobiliary unit were more likely to receive liver surgery and had improved median…

Intestine and Lower Gastrointestinal Tract18 Jun 2024

High Compliance with ERAS Protocol in Colorectal Surgery at Model 4 Hospital

ERAS protocol compliance at a model 4 hospital in Ireland was over 70%, with satisfactory adherence to elements like laparoscopic surgery and nutritional drinks. Areas needing improvement included postoperative antibiotics and preoperative gabapentin documentation. Educating and involving the multidisciplinary team can successfully implement ERAS protocol…