Using a posterior-first, 2-stage approach, researchers achieved consistent R0 resection of locally advanced primary and recurrent anorectal cancers involving the deep pelvic sidewall. All 10 patients in the study achieved R0 resection, although nine experienced complications, including gluteal wound issues. Four patients developed metastatic disease during follow-up, highlighting the importance of close monitoring. Overall, the […]
Category: Intestine and Lower Gastrointestinal Tract
Enhanced Recovery Programs and Colorectal Surgery Outcomes: reduces Racial Disparities in Complications, but not in Length of Stay
The study aimed to determine the impact of enhanced recovery programs on social vulnerability and race-related disparities in colorectal surgery outcomes. The researchers found no significant association between social vulnerability and length of stay, complications, or readmissions in either the enhanced recovery or non-enhanced recovery groups. Black race was associated with increased length of stay […]
Implementation of ERAS Protocols in Colorectal Surgery Yields Positive Outcomes
Despite advancements in surgical and anesthetic care, the implementation of Enhanced Recovery After Surgery (ERAS) protocols in colorectal surgery still provides benefits. This single-center study compared patients undergoing elective colorectal surgery under an ERAS program to those receiving standard care and found that ERAS led to a reduction in non-surgical complications, shorter length of stay, […]
Metachronous Para-aortic Lymphadenectomy in Colorectal Cancer: Surgical Management Improves Survival
The systematic review focused on the outcomes of metachronous para-aortic lymphadenectomy in colorectal cancer treatment. Surgical resection of metachronous para-aortic lymph node metastasis (m-palnm) was found to be the preferred management strategy in 64% of patients. Patients who underwent surgical management experienced longer disease-free survival and overall survival rates. However, the evidence available is limited, […]
Sacral Neuromodulation Shows Promise in Relieving Symptoms of Low Anterior Resection Syndrome
Sacral neuromodulation may be effective in relieving symptoms of low anterior resection syndrome after rectal cancer surgery, according to the SANLARS randomized clinical trial. The trial involved 46 patients, of whom 78% experienced a ≥50% reduction in symptoms after testing. During the crossover phase, all patients showed a reduction in symptoms, with better results when […]
Association Between RAS/BRAF Mutations and Lower Complete Response Rates in Rectal Cancer Patients
The study aimed to assess the impact of RAS/BRAF mutations on complete response rates after total neoadjuvant therapy (TNT) in advanced rectal cancer patients. Findings revealed that patients with mutant RAS/BRAF had significantly lower rates of achieving clinical and overall complete response compared to those with wild-type RAS/BRAF. However, there was no significant difference in […]
Quantitative Indocyanine Green Metrics Reliable for Intestinal Margin Acceptance in Colorectal Surgery
A study conducted at a tertiary academic center investigated the correlation between quantitative indocyanine green metrics and subjective indocyanine green perfusion assessment in determining the acceptance or rejection of anastomotic margins. The study included 89 perfusion assessments in 156 intestinal segments. The results showed that higher maximum fluorescence intensity and earlier time to maximum fluorescence […]
Optimizing Polyp Recurrence Prevention: Comparing Techniques in Colorectal EMR
A study compared different techniques for reducing recurrence rates after endoscopic mucosal resection (EMR) of large non-pedunculated colorectal polyps. The direct and indirect comparisons showed that EMR combined with submucosal tunneling endoscopic submucosal dissection (EMR+STSC) and underwater EMR (U-EMR) had significantly lower odds of polyp recurrence compared to EMR alone. The p-score ranking indicated that […]
Racial, Socioeconomic, and Insurance Disparities in Colon Cancer Care and Outcomes
Disparities in colon cancer care and outcomes exist based on race/ethnicity, socioeconomic status (SES), and insurance. Low-performing hospitals treat more non-Hispanic black, Hispanic, low SES, and Medicaid patients. Patients with low SES and Medicaid have decreased odds of receiving high-quality care at low-performing hospitals, while non-Hispanic black patients have decreased odds at high-performing hospitals. Low […]
Indocyanine Green Fluorescence Imaging Has No Impact on Mid-Term Outcomes of Laparoscopic Right-Sided Colectomy
In a retrospective cohort study, researchers evaluated the mid-term outcomes of indocyanine green fluorescence imaging-guided laparoscopic right-sided colectomy. After propensity score matching, they found that the number of dissected central, intermediate, and total lymph nodes was significantly higher in the indocyanine green group. However, there was no difference in the 3-year relapse-free survival and overall […]