A retrospective multicenter study compared the risk of distant metastases in rectal cancer patients who achieved a clinical complete response followed by local regrowth with those managed by surgery after chemoradiation. Out of 79 patients with local regrowth, 21 developed distant metastases, whereas only 10 out of 74 patients in the upfront surgery group had […]

Rectal stump leakage is a significant complication after discontinuity resection, with a rate of 11.78% in this study. The risk varies depending on the surgical procedure, and it was highest after subtotal pelvic exenteration. Researchers found that a shorter rectal stump, previous pelvic radiotherapy, chemotherapy, and previous laparotomy were independent risk factors for rectal stump […]

The study examined 68 surgical resections from patients with small bowel adenocarcinoma (SBA) to investigate the correlation between immunophenotypes, DNA mismatch repair status, genomic profiling, and clinicopathologic characteristics. The results showed that the expression of certain proteins correlated with tumor location, histologic type, and TNM stage. Muc1 and muc4 expression were associated with worse prognosis, […]

The study investigated the rate of proctectomy and rectal cancer among 197 familial adenomatous polyposis (FAP) patients selected for total abdominal colectomy with ileorectal anastomosis. The results showed that the incidence of proctectomy was 8%, with rectal cancer identified in 3% of cases. Patients with < 20 rectal polyps had a lower rate of proctectomy […]

Implementation of a multimodal prehabilitation program in colorectal surgery reduces postoperative complication rates, length of stay, and hospital costs. A study conducted in a regional Dutch hospital included 196 patients who completed prehabilitation and 390 patients who received standard care. The prehabilitation group had lower overall complication rates (31% vs. 40%) and severe complication rates […]

A retrospective study evaluated the efficacy of early contrast-enhanced CT scans for diagnosing anastomotic leakage (AL) after colorectal surgery in patients with elevated CRP levels. The study included 661 patients, with an overall AL rate of 7.4%, and found that early CT scans had an accuracy of 83.7% in diagnosing AL. The accuracy was lower […]

The study aimed to assess the impact of adding a lidocaine infusion for postoperative pain control in ERAS patients undergoing laparoscopic colectomy. The results of the retrospective review showed that patients who received the lidocaine infusion had a significant reduction in postoperative opioid use within the first 48 hours compared to those without it, with […]

Researchers conducted a retrospective population study to analyze the impact of surgical sub-specialization on short- and long-term outcomes in patients undergoing emergent surgery for colon cancer. The study included 656 patients divided into three groups based on specialization of the operating team. The results showed no significant differences in 5-year overall survival, 3-year recurrence-free survival, […]

This retrospective study investigated the surgical approach of total pelvic exenteration combined with sacral resection for rectal cancer and its impact on short-term outcomes. The association between the level of sacral resection and complications, specifically exhibiting a Clavien-Dindo grade III, was assessed. The results revealed a significantly higher complication rate for recurrent rectal cancer patients […]

The study analyzed the impact of an enhanced recovery protocol (ERP) on surgical outcomes in a high-risk population undergoing colon cancer surgery. Researchers retrospectively examined factors associated with postoperative complications (POC) and length of stay (LOS) in 408 elective colon cancer surgery patients. The results showed that ERP did not affect POC but was associated […]