The study investigated the metabolic changes and physiological factors mediating the effects of Roux-en-Y gastric bypass (RYGB) surgery in obese patients. Results showed that insulin concentrations decreased significantly after the surgery, along with improvements in weight loss and insulin sensitivity. Additionally, triglycerides, remnant cholesterol, lactate, glycoprotein acetyls, and certain amino acids decreased post-surgery. The study […]
Category: Metabolic and Bariatric Surgery
The Obesity Epidemic: Misconceptions and Harmful Beliefs
The CDC’s recent statements on obesity causing metabolic syndrome and attributing it to individual behavior are contested. Bariatric surgery outcomes challenge the direct link between obesity and diabetes suggested by the CDC. The rise in diabetes rates from 2004 to 2012 contradicts behavior-based explanations. The study emphasizes the need for a nuanced understanding of obesity […]
The Effect of Diet Composition on Post-operative Outcomes of Roux-en-Y Gastric Bypass in Mice: Key Findings
Regardless of diet, Roux-en-Y gastric bypass (RYGB) led to significant reductions in body weight, fat mass, and lean mass. RYGB and high-fat diet (HFD) independently affected bone mineral density and vitamin D levels. HFD after RYGB posed a significant health risk, impairing improvements to dyslipidemia, non-alcoholic fatty liver disease (NAFLD), and fibrosis. The study suggests […]
Comparable Outcomes of Gastric Bypass and Fundoplication for GERD in Patients with Obesity
A retrospective study compared the outcomes of Roux-en-Y gastric bypass and fundoplication in patients with obesity and gastroesophageal reflux disease (GERD). Ninety-five patients with a BMI ≥35 underwent either procedure. Both groups saw an improvement in GERD symptoms and overall quality of life. There were no significant differences in postoperative reflux symptoms, dysphagia, or overall […]
Metabolic surgery effectively resolves nonalcoholic steatohepatitis and improves fibrosis in patients with obesity
Metabolic surgery has been found to facilitate the resolution of nonalcoholic steatohepatitis (NASH) and improve fibrosis in patients with obesity. A study comparing the histologic outcomes of metabolic surgery versus nonsurgical care in individuals with fibrotic NASH revealed that half of the surgical patients achieved simultaneous resolution of NASH and improvement in fibrosis, compared to […]
Effect of Mood Disorders on Weight Loss Outcomes in Bariatric Surgery Patients
The study aimed to assess the impact of mood disorders on weight loss outcomes in patients undergoing bariatric surgery. Data from 775 patients were analyzed, out of which 38.1% had pre-existing mood disorder diagnoses. Both groups experienced significant reductions in postoperative body mass index, with no significant difference between the mood disorder group and the […]
Bariatric Surgery in ESRD Patients on Dialysis: Safety and Outcomes in the Transplant Era
Patients with end-stage renal disease (ESRD) on dialysis who underwent bariatric surgery experienced longer operative times and increased postoperative complications compared to those without renal disease. The study, analyzing data from the 2015-2020 MBSAQIP database, found that laparoscopic sleeve gastrectomy (LSG) and laparoscopic Roux-en-Y gastric bypass (LRYGB) were safe procedures for ESRD patients seeking kidney […]
Comparison of Single-Port and Multiple-Port Sleeve Gastrectomy: Feasibility and Non-Inferiority
Researchers investigated the feasibility of single-port sleeve gastrectomy (SPSG) by introducing a routine gastric suspension technique. Analyzing 171 patients, they compared SPSG to multiple-port sleeve gastrectomy (MPSG) and found no significant differences in preoperative and perioperative parameters, complications, or total weight loss percentages. SPSG demonstrated feasibility and non-inferiority compared to MPSG, suggesting its potential as […]
Effect of Bariatric Surgery on NAFLD/NASH: Improvement in Short-Term and Long-Term Outcomes
The prevalence of non-alcoholic fatty liver disease (NAFLD) is high in patients with obesity scheduled for bariatric surgery. This single-centre observational prospective cohort study aims to evaluate the impact of bariatric surgery on NAFLD/NASH. Initial findings show that bariatric surgery significantly improves NAFLD/NASH in the short term. However, the extent of this improvement and long-term […]
Efficacy of Nissen Sleeve Gastrectomy in Long-Term Barrett’s Esophagus Regression
Results of a bicentric retrospective study involving 692 patients who underwent Nissen Sleeve Gastrectomy (NSG) demonstrated that NSG led to the healing of known Barrett’s Esophagus (BE) in approximately 64.1% of patients at a 2-year follow-up. The incidence of de novo BE post NSG was found to be nil among the 234 patients who underwent […]