Patients with preoperative anemia undergoing curative-intent resection for gastroenteropancreatic neuroendocrine tumors (GEP-NETs) had higher rates of major complications and poorer long-term outcomes. Anemia was associated with worse overall survival, while postoperative transfusions were linked to lower overall survival and recurrence-free survival rates. Preoperative anemia affected around one-third of patients and significantly increased the risk of […]
Category: Sarcoma & rare tumors
Comparable Long-Term Survival Rates of Endoscopic Therapy and Surgical Resection for 2-5 cm Gastrointestinal Stromal Tumors
In a comparative study of endoscopic therapy (ET) versus surgical resection for 2-5 cm gastrointestinal stromal tumors, long-term outcomes showed no significant difference in overall or cancer-specific survival rates. After propensity score matching, both groups had comparable survival rates, suggesting that ET may be a viable treatment option for these tumors. Further research is needed […]
Frequency of size increase in gastric leiomyomas is low
Most gastric leiomyomas are benign subepithelial tumors, with few becoming symptomatic or increasing in size. A retrospective review of 231 cases showed that only 2.4% experienced size increase, one of which was leiomyosarcoma. The majority remained stable, with resections confirming leiomyoma. Close monitoring may be sufficient for asymptomatic cases, but resection could be considered for […]
Disparities in overall survival between rural and urban patients with pancreatic neuroendocrine tumors
Rural patients with pancreatic neuroendocrine tumors (pnets) have significantly shorter overall survival (OS) following primary pnet resection compared to urban patients. After adjustments for various factors, living in a rural area remained significantly associated with worse OS. This study highlights survival disparities between rural and urban pnet patients and emphasizes the need for targeted interventions […]
Prognostic Factors for Liver Metastasis in Small Intestinal Stromal Tumors
Researchers analyzed data from 1582 patients with small intestinal stromal tumors to identify risk factors for liver metastasis. They found that poor tumor grade, absence of surgery, later T-stage, and no chemotherapy were associated with an increased risk of liver metastasis. A nomogram prediction model showed good performance in predicting liver metastasis, and patients with […]
Textbook Outcome in Pancreatoduodenectomy for Nonfunctioning Pancreatic Neuroendocrine Tumors
Textbook outcome (TO) was achieved in one-third of patients after pancreatoduodenectomy (PD) for nonfunctioning pancreatic neuroendocrine tumors (NF-PANNETs). Tumor size, minimally invasive approach, and surgical volume were predictors of TO. TO was not associated with improved long-term survival, with similar rates seen in patients with and without TO. The TO rate was higher in patients […]
Radical resection favored for grade 2 rectal neuroendocrine tumors >1.5 cm
Comparing local excision and radical resection for grade 2 rectal neuroendocrine tumors showed no significant difference in survival for tumors ≤1.5 cm. However, tumors >1.5 cm had significantly lower relapse-free survival with local excision. Lymph node metastasis was present in 60% of patients who underwent radical resection. The study concluded that local excision is suitable […]
En-bloc resection of well-differentiated nonampullary duodenal neuroendocrine tumors is safe and effective
Endoscopic resection of well-differentiated nonampullary duodenal neuroendocrine tumors was safe and effective, with a high rate of en-bloc and R0 resections. Tumors located in the second part of the duodenum, ≥10mm in size, and with muscularis propria invasion were risk factors for non-curative resection. Adverse events were rare and successfully managed. Long-term outcomes showed low […]
Improvement in Clinical Outcomes and Diagnostic Accuracy with Multidisciplinary Management of Retroperitoneal Liposarcoma
Multidisciplinary team management in retroperitoneal liposarcoma treatment led to higher overall survival rates at 1, 3, and 5 years, improved diagnostic consistency, reduced perioperative mortality and postoperative complications, and enhanced disease awareness and postoperative compliance. The intervention showed significant benefits in clinical outcomes and diagnostic accuracy, highlighting the importance of multidisciplinary approaches in managing retroperitoneal […]
Identification of low-risk surgical candidates for small intestinal neuroendocrine tumors through combined imaging
A tailored diagnostic protocol using contrast-enhanced computed tomography enterography and 68 Ga dotatate PET/CT showed high sensitivity and specificity in detecting primary small intestinal neuroendocrine tumors (SI-NETs) and distal lymph node disease. The combined imaging allowed for the identification of low-risk surgical candidates with single SI-NET lesions and distal lymph node disease preoperatively, enabling potential implementation […]