Newsletter
Best Papers in General Surgery
The five that matter, every day.
A study analyzing over 14,000 minimally invasive esophagectomies reveals stark differences in perioperative mortality rates based on facility size. High-volume hospitals (≥30 procedures annually) boasted a much lower observed-to-expected mortality ratio (0.61) compared to smaller centers (
Analyzing data from over 33,000 patients, lymph node dissection demonstrates varying therapeutic value based on tumor location in non-metastatic colon cancer. The therapeutic value index (TVI) was highest for cecal and transverse cancers at specific nodal stations, indicating a need for tailored surgical strategies. Notably,…
Patients with preexisting chronic kidney disease (CKD) face a 26.6% rate of acute kidney injury (AKI) following abdominal wall reconstruction (AWR), compared to 11.8% for those with normal renal function. At one year, 6.9% of previously healthy individuals develop new CKD, while nearly 20% of…
Artificial intelligence is transforming endoscopic practices by surpassing human capabilities in polyp detection. Advanced systems, such as GI Genius, achieve high sensitivity and specificity in lesion identification, aiding the differentiation between benign and malignant growths. Additionally, AI streamlines workflows with automated reporting and enhanced training…
Surgical intervention for pancreatic adenocarcinoma markedly enhances survival rates in patients at all stages, except for those classified as stage IV with T4 or N1 classifications. A deep learning model, DeepSurv, demonstrated a robust c-index of 0.85 in predicting survival, with surgery notably lowering mortality…
A novel nomogram effectively predicts the risk of intestinal barrier dysfunction (IBDF) in patients post-major abdominal surgery. Analyzing 684 patients, researchers identified eight independent predictors, achieving an AUC of 0.946 in the training cohort and 0.944 in validation. This tool allows clinicians to identify high-risk…
Patients with locally advanced esophageal squamous cell carcinoma achieving neoadjuvant chemoradiotherapy followed by surgery experienced a median survival of 83.9 months, significantly surpassing outcomes of those treated with chemotherapy or definitive chemoradiotherapy, which recorded 27.8 and 26.5 months respectively. Propensity-matched analysis further confirmed the survival…
In managing severe cholecystitis, laparoscopic subtotal cholecystectomy and cholecystostomy tube placement yield lower bile duct injury rates compared to converting to open surgery. Analysis of nearly 385,000 laparoscopic cholecystectomies from 2012 to 2021 revealed a drop in conversion rates and an increase in subtotal cholecystectomy…
Patients with high pre-treatment CA19-9 levels show significantly poorer prognoses than those with normal levels. Neoadjuvant treatment (NAT) markedly enhances survival for these patients, with optimal outcomes for those achieving normalized CA19-9 or sufficient reduction post-treatment. Stratification reveals that patients with levels under 296 u/ml…
A newly validated nomogram accurately predicts postoperative recovery outcomes for patients undergoing pancreaticoduodenectomy for invasive intraductal papillary mucinous neoplasm (IPMN). Analyzing data from 479 patients, it identifies four key predictors: severe COPD, hypertension, elevated INR, and prolonged operative time, achieving a textbook outcome in roughly…
