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General Surgery

Best Papers in General Surgery

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Gut Microbes16 Sep 2025

Gut Microbiota Plays a Pivotal Role in Surgical Outcomes

The gut microbiome significantly influences recovery trajectories after surgery and trauma, reshaping patient outcomes beyond genetic predispositions. Individual life histories dictate microbiota composition, which can affect organ systems such as the liver, kidneys, and brain. This review shifts the focus from solely pathogenic bacteria to…

J Clin Med16 Sep 2025

Pancreatic Vascular Variations Crucial for Surgical Success

The intricate vascular anatomy of the pancreas, rife with variations, profoundly impacts surgical and interventional outcomes. Key arterial and venous structures, including the superior pancreaticoduodenal arteries and the gastrocolic trunk, require careful consideration to ensure effective surgical planning. Advances in imaging technologies now allow for…

Surg Endosc15 Sep 2025

More Than Half of Gas-Bloat Patients After Surgery Test Positive for SIBO

Over 56% of patients with persistent gas-bloat symptoms after antireflux surgery were SIBO-positive, experiencing significantly worse symptoms. After antibiotic treatment, severe bloating dropped from 77.5% to 23.1%, with substantial improvements in gas-bloat scores and patient satisfaction. SIBO testing emerged as a critical tool for diagnosing…

HPB & Spleen15 Sep 2025

Accelerated Management Cuts Treatment Times for Pancreatic and Liver Cancer

A streamlined approach to pancreatic and hepatocellular cancer treatment in Scotland significantly slashed the time from diagnosis to definitive treatment. Median treatment initiation for hepatocellular carcinoma (HCC) decreased from 98 to 62 days, while for pancreatic cancer (PC) the timeline shortened from 54 to 38…

Clin Res Hepatol Gastroenterol15 Sep 2025

Index Admission Cholecystectomy Cuts Mortality and Readmissions in Acute Cholangitis

Cholecystectomy performed during index admission for acute cholangitis significantly reduces in-hospital mortality and lowers 30- and 90-day readmission rates. In a study of over 29,000 patients, those who underwent surgery exhibited a 60% lower risk of death and nearly halved their likelihood of readmission compared…

Appendix, Gallbladder and Surgical Emergencies15 Sep 2025

Laparoscopic Repair Cuts Complications in Inguinal Hernia Surgery

Laparoscopic repair of incarcerated inguinal hernias, combined with an enhanced recovery after surgery (ERAS) protocol, significantly reduces postoperative complications. In a comparison involving 200 patients, those undergoing laparoscopy reported only 9% complications, compared to 38% in the open surgery group. This paradigm shift not only…

General Surgery15 Sep 2025

Strategies to Prevent Adhesions: What Every Surgeon Needs to Know

Adhesions are one of those surgical complications we’d all prefer to never think about—but we don’t get that luxury. They’re common, costly, and often underestimated. Whether it’s a patient returning with chronic abdominal pain, secondary infertility, or adhesive small bowel obstruction, adhesions remain a persistent…

Ann Coloproctol15 Sep 2025

Intracorporeal Anastomosis Cuts Incisional Hernia Risk in Laparoscopic Surgery

Intracorporeal ileocolic anastomosis (ICA) significantly reduces incisional hernia rates in laparoscopic right hemicolectomy compared to extracorporeal anastomosis (ECA). Despite a longer mean operative time (190 vs. 170 minutes), the 24-month hernia incidence plummeted to 1.2% with ICA versus 14.7% with ECA. Patients also benefited from…

BMC Surg14 Sep 2025

Wide Variation in Opioid Prescribing for Emergency Surgery Patients

Opioid prescribing in emergency general surgery varies significantly across hospitals, with discrepancies of 1.5 to 3.7 times in morphine equivalents. While most discharges follow elective guidelines (75%-96%), compliance drops sharply for colectomy, with only 4% adherence compared to 25% for appendectomy. Increased comorbidity and ASA…