A multi-omics analysis of ileal mucosa and mesentery samples from Crohn’s disease patients illustrates notable improvements in microbial health following ileocecal resection. Among 34 patients studied, significant spatial changes in microbiota and metabolites were identified pre- and post-surgery. Metabolites were further analyzed, revealing crucial insights into their roles. These findings underscore ileocecal resection as a […]
Category: General Surgery
Telemedicine expands oncology service capacity without increasing overall visits.
A significant growth in telemedicine utilization was observed in ambulatory surgical oncology at a high-volume academic center from 2019 to 2023. Overall visit volumes surged by 44%, while the clinician workforce increased by 16.8%. Unique patients served rose by 39%, primarily through enhanced return visits rather than new ones. Telemedicine adoption grew dramatically from 0.5% […]
AI Model Matches Senior Endoscopists in Esophageal Cancer Treatment
An artificial intelligence model developed for marking detection and incision guidance during esophageal endoscopic submucosal dissection (ESD) demonstrated promising performance. Compared to junior endoscopists, the AI achieved a notable accuracy of 63.21%, precision rates of up to 85.76%, and an average distance error of 0.096, significantly outperforming junior practitioners while matching senior endoscopists. These results […]
Digital tools enhance postoperative pain management at home
A scoping review of 26 studies reveals digital and telemedicine tools significantly improve postoperative pain management at home. These technologies, including mobile apps and wearable sensors, facilitate patient monitoring and communication with healthcare professionals, leading to better pain control, reduced opioid use, and high patient satisfaction. However, challenges such as low digital literacy among some […]
Immunotherapy-based regimens show promise in gastric cancer treatment
A meta-analysis of high-quality trials shows immunotherapy-based neoadjuvant regimens, particularly combining immunotherapy with chemotherapy and targeted therapy, significantly improve pathological complete response (PCR) rates and overall survival in locally advanced gastric cancer. The neoadjuvant immunotherapy plus chemotherapy (NICT) and NICT plus targeted therapy (NICTT) groups outperformed traditional chemotherapy, although the NICTT group faced increased severe […]
ERCP shows high success in managing traumatic pancreatic injuries
A systematic review revealed that endoscopic retrograde cholangiopancreatography (ERCP) achieves an impressive 89% success rate in treating traumatic pancreatic injuries (TPI). The procedure notably enhanced pancreatic duct integrity and led to lower complication rates (4-17%), primarily pancreatitis and bleeding. Mortality remained low at 3-5%, and ERCP significantly reduced hospital stays by an average of 3.1 […]
Bariatric surgery reduces risks in obese patients with CKD
In a comprehensive study of 5,221 adults with obesity and chronic kidney disease (CKD), bariatric metabolic surgery (BMS) demonstrated a significantly reduced risk of major adverse cardiovascular events, major adverse kidney events, and all-cause mortality over five years. The protective effects of BMS were consistent across all CKD stages but were notably stronger in patients […]
Advances in Third-Space Endoscopy Improve GI Tumor Management
A review highlighted significant advancements in third-space endoscopy techniques for gastrointestinal tumors. Submucosal tunneling endoscopic resection (STER) was found to be safe and effective, achieving high en bloc resection rates and reduced recovery times. Tunneling endoscopic submucosal dissection (ESD) variants also enhance outcomes for early neoplasms by improving dissection speed and minimizing adverse events. Incorporating […]
AI-assisted system effectively aids esophageal lesion resections
The implementation of an artificial intelligence (AI) lesion-labeling system significantly improved the complete resection rate during endoscopic submucosal dissection (ESD) in low-volume centers. In a study involving 174 patients, 90% achieved negative lateral margins, while the en bloc resection rate stood at 98.5%. Comparatively, no significant difference was found in the lateral resection rates between […]
Size cut-offs established for rectal neuroendocrine neoplasm recurrence
A recent retrospective study involving 1,011 patients identified critical size thresholds for rectal neuroendocrine neoplasms (NENs). For grade 1 tumors, a 0.7 cm cut-off showed 100% sensitivity and 79% specificity, indicating minimal recurrence risk. Conversely, grade 1 tumors with lymphovascular invasion necessitated a 1.5 cm cut-off. Grade 2 NENs, which exhibited a 22.9% lymph node […]