Newsletter
Best Papers in General Surgery
The five that matter, every day.
In a study of 43,126 patients who underwent pancreatectomy, 16.3% developed postoperative pancreatic fistula (POPF). Preoperative weight loss correlated with reduced odds of developing POPF (odds ratio 0.87), whereas higher body mass index (BMI) increased risk. For patients experiencing weight loss, each BMI point increase…
A novel prognostic nomogram has been developed for predicting overall survival (OS) and cancer-specific survival (CSS) in signet ring cell gastric cancer patients post-surgery. Analyzing data from 3,481 patients, researchers identified critical independent prognostic factors, including race, chemotherapy, and lymph node ratio. The nomogram demonstrated…
A comprehensive framework developed by the Society of Robotic Surgery outlines best practices for effective and ethical telesurgery. This initiative drew on extensive literature reviews and expert consensus from various disciplines. Key considerations encompass technological requirements, safety standards, training protocols, and legal issues. By promoting…
A novel predictive model for perforation risk during endoscopic submucosal dissection (ESD) has been developed and validated by researchers. In a study involving 1,051 patients, significant predictors included the first 100 procedures, lesion size over 35 mm, and extended operative time. The model demonstrated satisfactory…
A machine learning model significantly improves risk stratification for post-pancreaticoduodenectomy hemorrhage (pph), identifying eight key predictors such as albumin levels and operative time. With an area under the curve (AUC) of 0.84 during training and 0.82 in validation, this model outperformed traditional logistic regression, enabling…
A scoping review of 39 studies on acute mesenteric ischaemia indicated that endovascular interventions significantly improved patient outcomes. Notably, they showed lower 30-day mortality rates compared to open surgery, ranging from 0% to 53.8% versus 21% to 81%. Additionally, patients receiving endovascular treatment experienced shorter…
A recent meta-analysis indicates that pathological complete response (pCR) following neoadjuvant chemoradiotherapy significantly improves long-term survival outcomes in patients with locally advanced esophageal cancer undergoing surgery. Findings from 38 included studies revealed a hazard ratio of 0.54 for overall survival and 0.51 for disease-free survival…
A LASSO-based nomogram has been developed to predict anastomotic leakage (AL) in elderly patients undergoing laparoscopic gastrectomy. An analysis of 884 patients identified significant predictors, including age, ASA score, diabetes, intraoperative blood loss, and prognostic nutritional index. The nomogram demonstrated high predictive accuracy, achieving AUC…
Researchers developed online calculators to assess patients' likelihood of benefiting from liver resection for intrahepatic cholangiocarcinoma. Among 889 patients studied, the 90-day mortality rate was 8.5%, with median overall survival at 24.1 months. Risk profiles categorized patients into three groups: favorable (90-day mortality 4.3%, survival…
Cumulative sum analysis in laparoscopic pancreaticoduodenectomy showed that surgeon proficiency continues to evolve beyond the initial learning phase. In a review of 381 patients, significant improvements were noted across operative time, blood loss, length of stay, and postoperative complications over three defined phases. Notably, operative…
