Newsletter
Best Papers in General Surgery
The five that matter, every day.
In a systematic review of 12 studies involving 6,747 cases of hepatocellular carcinoma (HCC) with microvascular invasion, narrow resection margins (RMs) were identified as significant risk factors for postoperative recurrence and overall survival (OS). Researchers reported that narrow RMs had a pooled hazard ratio of…
A novel AI model named Coffee was developed to classify histopathological growth patterns in colorectal liver metastases, achieving impressive predictive performance with AUC values up to 1.000 in prospective cohorts. Desmoplastic tumors were linked to improved overall and progression-free survival compared to non-desmoplastic tumors. Additionally,…
A cutting-edge AI model demonstrated significant accuracy in detecting post-hepatectomy liver failure (PHLF) within the first 24 hours post-surgery. The model achieved an AUC of 0.952 in internal validation and 0.884 in external validation among 1,832 patients across six Chinese hospitals. Moreover, it outperformed existing…
A recent population-based study found that higher scores on life's essential 8 (LE8), a cardiovascular health metric, significantly correlate with a reduced prevalence of colorectal cancer (CRC) among U.S. adults. Those with the highest LE8 scores experienced an 81% lower risk of CRC compared to…
The PANDRA II trial revealed that patients undergoing left pancreatectomy without routine abdominal drainage had similar morbidity rates compared to those with drainage. The no-drain group demonstrated noninferiority in overall postoperative morbidity, with a comprehensive complication index of 13.90 versus 19.43 for the drain group…
A dual-center study involving 69 patients demonstrated that near-infrared fluorescence imaging (NIRF) combined with Sonazoid contrast-enhanced ultrasound (SCEUS) significantly improves the detection of colorectal liver metastases (CRLMs) during laparoscopic surgery. NIRF+SCEUS identified 285 lesions, outpacing the 234 detected by white light and intraoperative ultrasound. Notably,…
A recent network meta-analysis evaluated prehabilitation strategies for patients undergoing digestive system cancer surgery. It involved 26 randomized controlled trials with 2042 patients, revealing significant benefits: a 1.12-day reduction in hospital stay and decreased postoperative complications by 29%. Exercise-based prehabilitation emerged as the top intervention,…
A comprehensive study analyzing 5,726 patients with obstructive jaundice has identified key etiologies, revealing cholangiocarcinoma, pancreatic adenocarcinoma, and common bile duct stones as predominant causes. Despite traditional markers lacking accuracy, two machine learning models were successfully developed, achieving an area under the receiver operating characteristic…
Peritoneal metastasis from gastric cancer significantly impacts prognosis, but advancements in diagnostic and therapeutic strategies are transforming patient outcomes. A peritoneal cancer index (PCI) threshold of ≤6 identifies patients with oligometastasis who may benefit from aggressive therapies. Cytoreductive surgery coupled with hyperthermic intraperitoneal chemotherapy remains…
A retrospective analysis reveals augmented reality (AR) enhances tumour localisation in minimally invasive liver surgery (MILS), achieving a zero conversion rate for the AR group, compared to six conversions in the non-AR group. While AR increased operative times by 10%, it did not adversely affect…
