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General Surgery

Best Papers in General Surgery

The five that matter, every day.

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Upper Gastrointestinal Tract13 Jul 2025

Psychological and sleep interventions enhance recovery in gastric cancer patients

A study involving 198 postoperative gastric cancer patients reveals a structured psychological and sleep enhancement program significantly reduces anxiety, depression, and perceived stress while improving sleep quality. After three months, immune function and inflammatory markers also showed notable improvements. Patients in the intervention group experienced…

J Surg Res13 Jul 2025

High-fidelity simulation improves surgical trainees’ confidence in trauma procedures

A new high-fidelity simulation model, known as OS3, significantly boosts surgical trainees' confidence and skills in managing vascular trauma. Analysis of surveys from 183 participants revealed that increasing postgraduate years correlated with higher self-assessments of knowledge and skills. Despite this, many trainees reported difficulties with…

Ann Gastroenterol Surg13 Jul 2025

Novel surgical technique preserves ghrelin secretion in gastric cancer

A new surgical approach, super subtotal gastrectomy (SSTG), effectively preserves the fornix, a vital site for ghrelin secretion, in patients with upper-third gastric cancer. This innovative technique minimizes the typical impacts on appetite and weight loss associated with traditional proximal gastrectomy or total gastrectomy. In…

Innov Surg Sci13 Jul 2025

New deep learning models excel in organ donation image segmentation

Deep learning models, detectron2 and yolov8, significantly improved automated segmentation in organ donation photography, achieving internal validation Intersection over Union (IoU) scores of 0.93 and 0.94 for kidneys, and 0.97 for livers. Compared to traditional methods, which peaked at IoU 0.54, these new models demonstrated…

J Surg Res12 Jul 2025

Smoking increases surgical site infection risk in trauma patients

A significant association between smoking and surgical site infections (SSI) was identified in trauma patients, with 24.3% of those studied being smokers. Compared to nonsmokers, smokers had higher SSI rates (0.9% vs. 0.7%) and an increased risk persisted even after controlling for confounding factors. The…

BMC Gastroenterol12 Jul 2025

Surgical treatment for hemorrhoids offers better outcomes

A meta-analysis of seven studies involving 760 patients demonstrates that surgical intervention for hemorrhoids significantly surpasses conservative methods in achieving complete symptom resolution (odds ratio = 2.96, p < 0.001) and reducing pain scores (standard mean difference = -0.93, p = 0.02). Though both treatment…

Therap Adv Gastroenterol12 Jul 2025

Hydrogels may reduce esophageal stricture risk post-ESD.

Innovative hydrogel interventions show promise in significantly reducing stricture rates following endoscopic submucosal dissection for early esophageal cancer. Current methods have limited effectiveness and safety concerns, but hydrogels offer biocompatibility and enhanced therapeutic delivery. They promote epithelial regeneration and reduce fibrosis, potentially improving long-term outcomes.…

EClinicalMedicine12 Jul 2025

Etomidate-opioids show promising sedation balance for endoscopy

A systematic review and network meta-analysis of 152 trials involving 26,527 patients reveals no pharmacological regimen superior to propofol-opioids for sedation success in gastrointestinal endoscopy. However, etomidate-opioids ranked highest for sedation success, bradycardia, and recovery time, significantly reducing hypoxia risk compared to propofol-opioids. Esketamine-remimazolam exhibited…

Ann Coloproctol12 Jul 2025

Mosapride accelerates recovery of gastrointestinal motility post-surgery

Mosapride significantly enhances gastrointestinal recovery following elective colorectal cancer surgery. In a randomized controlled trial involving 44 patients, those receiving mosapride experienced their first bowel movement in an average of 26 hours compared to 50 hours for the control group (p=0.004). Similarly, the time to…

Ann Surg Oncol11 Jul 2025

New guidelines prioritize systemic therapy for colorectal cancer with peritoneal metastases

Consensus guidelines for managing colorectal cancer with peritoneal metastases emphasize early referral to specialized centers. A national panel achieved over 90% consensus on clinical pathways, favoring systemic therapy over upfront surgery in synchronous cases. In metachronous cases, risk stratification was updated. Although the overall evidence…