Innovative hydrogel interventions show promise in significantly reducing stricture rates following endoscopic submucosal dissection for early esophageal cancer. Current methods have limited effectiveness and safety concerns, but hydrogels offer biocompatibility and enhanced therapeutic delivery. They promote epithelial regeneration and reduce fibrosis, potentially improving long-term outcomes. This review highlights the transformative potential of hydrogels in clinical practice, suggesting a pivotal shift toward more effective management of post-ESD complications.
Review by Wu J, Guo CG (…) Li P et 3 al. in Therap Adv Gastroenterol
© The Author(s), 2025.