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General Surgery

Best Papers in General Surgery

The five that matter, every day.

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Gut5 Jun 2025

Guidance aids decision-making for managing colorectal polyps

Guidelines developed by the BSG/ACPGBI assist clinicians in managing colorectal polyps for patients with a life expectancy of under 10 years. The guidance outlines 33 recommendations drawn from a consensus process involving 28 experts. It includes assessments of life expectancy, polyp characteristics, and risks of…

Gastrointest Endosc5 Jun 2025

EMR shows lower mortality and healthcare utilization than surgery

In a comparative study of colon adenomas and early-stage cancers, endoscopic mucosal resection (EMR) significantly outperformed traditional surgery. Among 568 EMR patients and 2,054 surgical patients, EMR was associated with a lower all-cause mortality rate (hazard ratio 0.31) and reduced healthcare utilization over an average…

BMC Gastroenterol5 Jun 2025

Predictive model for liver metastasis risk in AEG patients

A novel nomogram accurately predicts the risk of postoperative liver metastasis in patients with adenocarcinoma of the esophagogastric junction (AEG) based on six independent factors: type of surgery, N stage, tumor differentiation, vascular thrombus, intestinal type, and p53 status. High predictive accuracy was demonstrated with…

Int J Surg5 Jun 2025

Key predictors identified for laparoscopic appendectomy conversion

A systematic review of 45 studies with over 3.2 million cases revealed an 8.7% conversion rate from laparoscopic to open appendectomy. Key risk factors included older age, male gender, and comorbidities such as obesity and diabetes. Other significant predictors were previous abdominal surgery, prolonged symptom…

Int J Surg5 Jun 2025

Fully-covered metal stents outperform plastic for biliary drainage

A comprehensive review of 81 studies with 26,251 patients reveals that fully-covered self-expandable metal stents used during endoscopic retrograde cholangiopancreatography result in fewer adverse events compared to plastic stents, though they carry a higher risk of pancreatitis. Plastic stents resulted in more complications and shorter…

Ann Surg Oncol4 Jun 2025

High Postoperative IL-6 Levels Deteriorate Outcomes in Esophageal Cancer

Elevated serum interleukin-6 (IL-6) levels one day post-minimally invasive esophagectomy (MIE) correlate with significantly poorer overall survival rates and nutritional status in esophageal cancer patients. In a cohort of 336 patients, those with IL-6 levels ≥60 pg/ml exhibited a 2-year overall survival rate of 69.8%,…

Dis Colon Rectum4 Jun 2025

Emergency resection increases complications and mortality in colon cancer

A recent analysis of 5,056 patients with right-sided colon cancer revealed that emergency resections lead to significantly higher mortality rates (9.4% vs 4.2%) and complication rates (41.7% vs 33.0%) compared to elective resections. While anastomotic leakage rates remained statistically similar, the findings suggest that emergency…

J Surg Res4 Jun 2025

Standardized reporting enhances understanding of surgical outcomes

A trauma center's initiative to standardize morbidity and mortality conferences resulted in the documentation of 916 patient events. With 65% of these being trauma-related, the program utilized a quality of care score to facilitate analysis. Notably, trainee and consensus scores matched in 84% of instances,…

World J Surg Oncol4 Jun 2025

Preoperative embolization with thermal ablation is effective

Combining preoperative trans-arterial embolization with thermal ablation shows promise in treating large hepatic hemangiomas, achieving a 100% lesion coverage rate. Among 82 patients followed for up to 48 months, minor complications occurred in 65.9% of cases, with no severe complications reported. The median operating time…

Medicine (Baltimore)4 Jun 2025

Combination of omega-3 PUDAs and alanyl-glutamine enhances recovery

Alanyl-glutamine and omega-3 polyunsaturated fatty acids positively influenced postoperative outcomes in patients with gastroduodenal perforations. In a study involving 168 patients, those receiving the combination therapy experienced significant increases in total protein and albumin levels, alongside reduced C-reactive protein levels, indicating lower inflammation. Notably, group…