Newsletter
Best Papers in General Surgery
The five that matter, every day.
A multicenter study with 5,774 hepatocellular carcinoma (HCC) patients with hypohepatia revealed that liver resection (LR) provides significant survival advantages compared to ablation and transarterial chemoembolization (TACE). The findings showed that LR led to lower risks of death and disease progression across various subgroups, making…
A systematic review of 11 studies revealed that non-pharmacological interventions in Sub-Saharan Africa significantly decrease surgical site infections (SSI) by 15% to 95%. These interventions included improving adherence to protocols, policy changes, and implementing multimodal strategies. The effectiveness of these approaches varied based on patient…
A study involving 639 rectal cancer patients identified key preoperative risk factors for permanent stoma post-sphincter-preserving surgery. Notably, 11.9% of patients developed a permanent stoma within two years. Factors such as male sex, tumor height, and the presence of synchronous liver or lung metastases were…
Findings indicate that mesenteric edema and abnormal bowel wall thickening serve as sensitive and specific indicators for both non-necrotic and necrotic small bowel strangulation (SBS). In a study involving 141 SBS patients, these indicators were significantly less frequent in cases of simple bowel obstruction. Notably,…
An updated risk prediction model for pancreaticoduodenectomy was developed using data from 35,365 patients in Japan. The study identified 28 factors for surgical mortality and severe complications, and 14 for postoperative pancreatic fistula. The model demonstrated a favorable predictive capability with area under the curve…
Key findings reveal that specific patient characteristics, including race, body mass index (BMI), diabetes, chronic obstructive pulmonary disease (COPD), gastroesophageal reflux disease (GERD), and therapeutic anticoagulation, are linked to elevated 30-day readmission rates following metabolic surgery. Notably, black and Hispanic patients showed increased odds of…
A randomized controlled trial involving 69 patients demonstrated that the sequential injection-electrocoagulation method significantly reduced the median time to hemostasis during endoscopic submucosal dissection (17 seconds) compared to traditional electrocoagulation (22 seconds), with p < 0.001. The experimental method also yielded higher visibility scores (3.24…
Findings emphasize the importance of mismatch repair (MMR) protein expression in tumors, linking it to microsatellite instability (MSI) and its implications for colorectal and endometrial cancers. Loss of MMR status signifies potential treatment strategies for patients, helping clinicians in tailoring interventions to individual tumor profiles.…
A study utilizing data from 7,463 pancreatic neuroendocrine tumor (PanET) patients developed a gradient boosting machine (GBM) model, marking it as the most effective tool for predicting liver metastasis. The model achieved an AUC of 0.937 and an accuracy of 0.87, highlighting independent risk factors…
A multicenter real-world study analyzed rectal resections in 829 patients, revealing notable outcomes for robotic-assisted surgeries. This group experienced shorter hospital stays, less blood loss, and fewer postoperative complications compared to laparoscopic and open surgery techniques, while also achieving lower rates of positive circumferential resection…
