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Best Papers in General Surgery
The five that matter, every day.
A comparison of minimally invasive surgery (MIS) and open radical cholecystectomy for gallbladder cancer revealed no significant difference in mortality or major morbidity. However, MIS patients experienced shorter hospital stays and lower rates of blood transfusions and superficial surgical site infections. Specifically, the average hospital…
A study found that the subcostal dual laparoscopic-assisted transversus abdominis plane block significantly reduced morphine requirements and improved recovery quality compared to ultrasound-guided techniques and placebo for patients undergoing pfannenstiel incision. The analysis showed an absolute difference of -8.9 mg and -10.3 mg in morphine…
A combination of Milligan-Morgan hemorrhoidectomy with rubber band ligation and polidocanol foam sclerotherapy significantly lowers recurrence rates and enhances patient satisfaction compared to traditional hemorrhoidectomy. In a study involving 255 patients, the MMH + RBL + PFS group evidenced a recurrence rate of just 0.78%, versus 7.09% with standard…
A study involving 329 patients with acute intestinal obstruction revealed that 11.25% developed postoperative incisional infections, primarily caused by gram-negative bacteria like Escherichia coli. High resistance rates to ceftriaxone were noted. Researchers developed a predictive model using six significant variables: age ≥ 60 years, diabetes,…
A new surgical technique using omental wrapping and stenting around pancreaticojejunal anastomosis significantly reduced postoperative complications. In a study of 48 patients undergoing pancreaticoduodenectomy, group B, which received the omental flap and stent, showed lower rates of pancreatic fistula (4.2% vs. 20.8%), hemorrhage, biliary fistula,…
A study involving 230 Chinese patients with colorectal liver metastasis identified significant predictors for chemotherapy response. Key factors included gender, the use of biological targeted agents (BTAs), and specific mutations in the KRAS gene and other rare genes. A predictive model achieved an area under…
A multicenter study found that transoral septotomy (TS) and Z-POEM treatments for Zenker diverticulum yield similarly high success rates of 96.2%. While TS requires a shorter operative time and has fewer intraoperative complications, both methods resulted in favorable outcomes and significant symptom relief after a…
A study involving 220 patients revealed that KRAS mutations negatively affect long-term outcomes after thermal ablation (TA) and liver resection (LR) for colorectal liver metastases (CRLM). Among patients with mutated KRAS, factors like synchronous disease and the performance of multiple TAs significantly influenced disease-free survival.…
An innovative online nomogram has been developed to predict the risk of lymph node metastasis (LNM) in colon cancer patients, enhancing treatment decision-making. Built on data from 412 patients, the model identified eight key independent predictors, demonstrating high discriminative ability with AUCs of 0.834 and…
The immune prognostic index (ipi) effectively predicts prognosis and the benefit of postoperative chemotherapy in esophageal squamous cell carcinoma (ESCC) patients following minimally invasive esophagectomy (MIE). Patients with a low ipi demonstrated significantly better 5-year overall survival (OS) and disease-free survival (DFS) compared to those…
