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General Surgery

Best Papers in General Surgery

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Gastrointest Endosc8 May 2025

Conventional techniques effectively manage previously partially resected colorectal lesions

Findings indicate that conventional endoscopic resection techniques can safely and effectively handle previously partially resected colorectal polyps. Out of 220 such lesions, all were successfully resected with similar recurrence rates (8.2%) compared to lesions without prior resection (7.8%). Notably, previously resected lesions required more advanced…

J Am Coll Surg8 May 2025

ACS model offers fastest surgical care for cholecystectomy

Analysis of 2,247 cholecystectomy cases reveals that patients under acute care surgery (ACS) models experienced significantly quicker surgery times, with a median interval from admission of just 25.1 hours. In contrast, other practice models reported longer times, up to 61.1 hours. ACS patients also had…

Ann Surg Oncol8 May 2025

Joint nasogastric tube proves superior for esophagojejunostomy

A novel joint nasogastric tube (JNT) significantly improved the success rate of tube insertion into the esophageal stump during overlap-esophagojejunostomy, reaching 90.6% compared to 58.5% with traditional nasogastric tubing (TNT). Insertion times decreased dramatically, with JNT taking only 15 seconds versus 100 seconds for TNT.…

Int J Surg8 May 2025

Same-day discharge is as safe as inpatient stay for LSG.

A systematic review and meta-analysis involving 138,001 patients compared same-day discharge (SDD) laparoscopic sleeve gastrectomy (LSG) with inpatient (IP) procedures. Findings revealed SDD resulted in significantly fewer emergency room visits versus IP (odds ratio 1.52). No significant differences were found in readmission (odds ratio 1.48)…

Endocrine Surgery8 May 2025

Minimally invasive parathyroidectomy under local anesthesia is effective.

A systematic review of 23 studies involving 2,470 adults with primary hyperparathyroidism demonstrated the feasibility of minimally invasive parathyroidectomy under local anesthesia. Operative times averaged 43.86 minutes with a 95-97% success rate. Patients experienced a mean hospitalization of just 16.83 hours and relatively few complications.…

N Engl J Med7 May 2025

Neoadjuvant PD-1 blockade facilitates nonoperative management in early-stage tumors

In a phase 2 study involving 117 patients with early-stage mismatch repair-deficient solid tumors, neoadjuvant dostarlimab led to high rates of clinical complete responses. Specifically, all patients in cohort 1 with locally advanced rectal cancer opted for nonoperative management. Among cohort 2, 35 out of…

J Gastrointest Surg7 May 2025

Opioids can be safely omitted after major surgeries.

A protocol to eliminate routine opioid prescriptions for patients after major intra-abdominal surgery resulted in a significant decrease in post-discharge opioid use. Only 17% of patients in the intervention group received opioids within thirty days compared to 46% in the control group (p

Eur J Surg Oncol7 May 2025

ChatGPT-4o is superior in aiding gastric cancer decisions

ChatGPT-4o significantly outperformed Gemini Advanced in generating treatment recommendations for advanced gastric cancer, as evidenced by a structured evaluation of responses to ten clinical questions. It provided superior recommendations in surgical suggestions and chemotherapy options during multidisciplinary team discussions. Additionally, it excelled in analyzing rare…

Therap Adv Gastroenterol7 May 2025

Complete closure reduces delayed postpolypectomy bleeding risk.

In a study analyzing 1,259 colorectal polyps from 1,025 patients, complete closure using titanium clips significantly reduced the incidence of delayed postpolypectomy bleeding (DPPB) to 3.6%. Factors influencing DPPB included male gender and polyp size, both immutable, while incomplete closure presented a higher risk. Logistic…