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Best Papers in General Surgery
The five that matter, every day.
A 22-year retrospective study of 1,197 ulcerative colitis patients reveals that the introduction of biological agents has drastically cut colectomy rates from 12% to 2%. This major finding underscores the importance of achieving mucosal remission and maintaining low CRP levels to further reduce the necessity…
Active wound dressings significantly reduce postoperative pain and accelerate wound healing in patients following anorectal surgery. In a study with 110 participants, pain scores were notably lower in those receiving active dressings on days 1, 3, and 7 post-operation. Furthermore, the wound healing rates were…
A systematic review of 34 studies on post-hepatectomy liver failure (PHLF) models reveals a troubling risk of bias across all analyses. While most models utilized diverse predictive data types, their validation performance lagged significantly behind development metrics. The area under the curve for training models…
Findings indicate that age (≥45 years), male sex, and certain baseline colonoscopic findings are critical predictors of metachronous advanced colorectal adenomas post-polypectomy. Among 2,013 patients, those with multiple small or advanced adenomas showed significantly higher risks, with odds ratios of 3.27 and 5.41, respectively. These…
A systematic review and meta-analysis of 22 studies involving 1,812 patients revealed gabapentin's significant efficacy in postoperative pain management for abdominal surgery. It notably decreased pain levels, opioid consumption, and rates of postoperative nausea and vomiting (PONV), positioning gabapentin as a beneficial component of enhanced…
A novel multivariable model combining aspartate aminotransferase to platelet ratio and albumin-bilirubin grade effectively predicts clinically significant posthepatectomy liver failure (PHLF) in over 12,000 patients. With an area under the curve (AUC) of 0.77 in the prediction cohort and 0.74 in validation, its performance matches…
A study analyzing 694 patients undergoing esophagectomy for esophageal squamous cell carcinoma revealed that smokers faced significantly higher rates of major complications and 30-day mortality compared to non-smokers. Major morbidity rates reached 37% among smokers versus 23% for non-smokers. Active smokers experienced more severe pulmonary…
A systematic review and meta-analysis revealed that minimally invasive surgery (MIS) for acute groin hernias significantly reduces the rates of bowel resection, superficial surgical site infections, and hospital length of stay compared to traditional open surgery. Although both approaches showed similar results regarding operation duration,…
A newly developed preoperative risk score accurately predicts 90-day mortality in patients undergoing major liver resection, identifying five key factors: age ≥ 65 years, type 2 diabetes, primary liver cancer diagnosis, an American Society of Anesthesiologists score of ≥ 3, and extended hemihepatectomy. The score…
A study analyzing 952 laparoscopic common bile duct explorations found an impressive success rate of 89.2%. However, factors like older age, higher American Society of Anesthesiologists (ASA) scores, and the presence of larger or previously identified stones were linked to undesirable outcomes. Surgeons developing their…
